Results 41 to 50 of about 839,014 (230)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Ideals and congruences in $L$-algebras and pre-$L$-algebras [PDF]
Categories and General Algebraic Structures with ApplicationsWe link the recent theory of $L$-algebras to previous notions of Universal Algebra and Categorical Algebra concerning subtractive varieties, commutators, multiplicative lattices, and their spectra.
Marino Gran +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Persistence and stability properties of powers of ideals [PDF]
, 2012 We introduce the concept of strong persistence and show that it implies persistence regarding the associated prime ideals of the powers of an ideal. We also show that strong persistence is equivalent to a condition on power of ideals studied by Ratliff ...
Herzog, Jürgen, Qureshi, Ayesha Asloob
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Positive Gorenstein Ideals [PDF]
, 2012 We introduce positive Gorenstein ideals. These are Gorenstein ideals in the graded ring $\RR[x]$ with socle in degree 2d, which when viewed as a linear functional on $\RR[x]_{2d}$ is nonnegative on squares.
Blekherman, Grigoriy
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Properties of Neutrosophic κ- bi-ideals in near-subtraction semigroups [PDF]
Neutrosophic Sets and SystemsThis paper presents the concept of neutrosophic κ-bi-ideals within the framework of nearsubtraction semigroups and explores the associated findings. The concept of neutrosophic intersections is explored.
B. Elavarasan +3 more
doaj
Prime preideals on bounded EQ-algebras
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2022 EQ-algebras were introduced by Novák in [14] as an algebraic structure of truth values for fuzzy type theory (FFT). In [1], Borzooei et. al. introduced the notion of preideal in bounded EQ-algebras.
Akhlaghinia N. +2 more
doaj +1 more source