Results 151 to 160 of about 9,355,935 (293)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Structural social factors modify the association between Alzheimer's pathology and cognitive function. [PDF]

J Prev Alzheimers Dis
Gerards M, Sannemann L, Jessen F.
europepmc   +1 more source

How Ideas Spread: Whose Norms Matter? Norm Localization and Institutional Change in Asian Regionalism

International Organization, 2004
Amitav Acharya
semanticscholar   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

The institutional dynamics of inequality for women inventors who break with conventional thinking. [PDF]

Proc Natl Acad Sci U S A
Sowrirajan T, Whalen R, Uzzi B.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Cost of an Audit and Feedback intervention to increase uptake of maternal and child health services in Mozambique's Primary health care. [PDF]

Implement Sci Commun
Birru E, Dinis A, Crocker J, Fernandes Q, Gimbel S, Gloyd S, Gremu A, Hirschhorn LR, Ramiro I, Tembe S, Augusto O, Sherr K.   +11 more
europepmc   +1 more source

From ideas to efficacy: The ORBIT model for developing behavioral treatments for chronic diseases.

Health Psychology, 2015
Susan M Czajkowski, L. H. Powell, Nancy Adler, Sylvie Naar-King, K. Reynolds, Christine Hunter, Barbara A. Laraia, Deborah H Olster, Frank M Perna, J. Peterson, E. Epel, Josephine E Boyington, M. Charlson   +12 more
semanticscholar   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Co-Creating Organisational Health Literacy: Formative Evaluation and Feasibility Testing of OHL-Act. [PDF]

Int J Environ Res Public Health
Renneberg CK, Rasmussen ASD, Meldgaard M, Maindal HT, Aaby A.   +4 more
europepmc   +1 more source