Results 131 to 140 of about 4,350,325 (326)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Oil Identification of harp seal and other select marine mammals

Forensic Science International: Animals and Environments
Because of the rich omega-3 fatty acids content, harp seal (Pagophilus groenlandicus) oil is a popular supplement that is packaged as pills in Canada and sold for medicinal purposes, although this practice is banned in the United States.
Megahn H. Pinedo, Deborah A. Duffield, Dalin N. D’Alessandro, Erin R. Price, Edgard O. Espinoza   +4 more
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

A network-biology approach for identification of key genes and pathways involved in malignant peritoneal mesothelioma [PDF]

, 2021
A. M. U. B. Mahfuz, A. M. Zubair-Bin-Mahfuj, Dibya Joti Podder   +2 more
openalex   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

How New Insights in the Biology of Brain Metastases May Lead to the Identification of New Effective Medical Therapies [PDF]

, 2012
Brunilde Gril, Thomas Bachelot, Gilles Romieu, Claire Cropet, Mario Campone, Véronique Dièras, Mónica Jiménez, Florence Dalenc, Émilie Le Rhun, C. Labbé-Devilliers, Frank J. Lagerwaard   +10 more
openalex   +1 more source

Meloidogyne graminicola—A Threat to Rice Production: Review Update on Distribution, Biology, Identification, and Management [PDF]

, 2021
Leidy Rusinque, Carla Maleita, Isabel Abrantes, Juan E. Palomares‐Rius, Maria L. Inácio   +4 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Erratum to: Identification of uncultured bacteria tightly associated with the intestine of the earthworm Lumbricus rubellus (Lumbricidae; Oligochaeta) [Soil Biology & Biochem. 35(12):1547–55]

, 2004
David R. Singleton, Paul F. Hendrix, David C. Coleman, William B. Whitman   +3 more
openalex   +1 more source

Network Biology led identification of critical miRNA modules for High Altitude hypoxia and their potential as dietary supplements [PDF]

, 2021
Apoorv Gupta, R. Sugadev, Y. K. Sharma, Pankaj Khurana   +3 more
openalex   +1 more source