Results 231 to 240 of about 5,558,675 (362)

Systems Biology Approach to Identification of Novel Drug Targets for Mycobacterium tuberculosis Infection

, 2014
Sarah Helmy
openalex   +2 more sources

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Human tick biting and tick-borne disease risk in Türkiye: Systematic review. [PDF]

PLoS Negl Trop Dis
Ahrabi SZ, Pınarlık F, Akyıldız G, Kuşkucu M, Kar S, Ergönül Ö, Keleş AG, TEH Vector-Borne Infections Study Group.   +7 more
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Metabolic and immune heterogeneity in stroke: Insights into subtype identification and biomarker discovery. [PDF]

PLoS One
Wang W, Qian Q, Guo Z, Lin F, Lin W, Yuan Z, Shen M.   +6 more
europepmc   +1 more source

Identification, Biology, and Control of Small-Leaf Spiderwort (Tradescantia fluminensis): A Widely Introduced Invasive Plant

, 2016
Jason C. Seitz, Mark Clark
openalex   +2 more sources

Identification and Analysis of Transcriptional Regulatory Networks of Osteosarcoma Microarray Data via Systems Biology

, 2022
Jun Cai, Zhiwei Tao, Xin Chen, ende Yi
openalex   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Atherosclerosis is associated with amyloid and tau pathology via blood-brain barrier dysfunction in the hippocampus of aged human brains. [PDF]

PLoS One
Jin Z, Liu N, Wei H.
europepmc   +1 more source

In-silico Identification of Novel Drug Target for Osteoarthritis using Network Biology Approaches

, 2022
Nityendra Shukla, Neha Srivastava, Aditya Trivedi, Prahlad K. Seth, Prachi Srivastava   +4 more
openalex   +1 more source