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DWARF BUNT: Politics, Identification, and Biology
Annual Review of Phytopathology, 1996▪ Abstract Dwarf bunt is a disease of wheat caused by the smut fungus Tilletia controversa Kuhn. Winter wheat (Triticum aestivum L.) is the primary host of economic significance. Although the total acreage affected by dwarf bunt is small relative to total wheat production worldwide, the disease has assumed attention disproportionate to its economic ...
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SYSTEM IDENTIFICATION CHALLENGES FROM SYSTEMS BIOLOGY
IFAC Proceedings Volumes, 2006Abstract Systems biology is the understanding through computational modelling of the function of biological systems. New high-throughput experimental technologies can measure simultaneously the levels of expression of thousands of genes. The challenge is to extract knowledge from these data sets in order to understand the regulatory machinery of the ...
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Psychiatric Disorders Biomarker Identification: from Proteomics to Systems Biology
Pharmacopsychiatry, 2008The pathobiology of psychiatric disorders remains mostly obscure. Diagnosis is often imprecise and current treatments are empirical and at best symptomatic. The identification of biomarkers can help with developing improved drugs and establishing more precise disease diagnoses.
Reckow, S. +3 more
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Structural Biology for Target Identification and Validation
Structural biology is catalyzing a paradigm shift in drug discovery towards rational approaches in target identification and validation. Leveraging structural insights obtained through cryo-EM or X-ray crystallography not only enhances the efficiency of drug discovery projects in terms of time and cost, but also significantly improves the likelihood ofYuliya, Dubianok +2 more
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Applications of Nonlinear System Identification in Molecular Biology
2006 International Conference of the IEEE Engineering in Medicine and Biology Society, 2006Here we show how nonlinear system identification techniques, such as fast orthogonal search (FOS) and the orthogonal search method (OSM), can be used to analyze gene expression profiles and predict the class to which a profile belongs.
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Sweetpotato Insects: Identification, Biology and Management
2009Sweetpotato, Ipomoea batatas originated in northwestern South America around 8000–6000 Bc (Austin, 1988). Sweetpotato ranks seventh among all food crops worldwide, with an annual production of 115 million MT (FAO, 1980). Approximately 92% of the world’s sweetpotato is produced in Asia and the Pacific islands; 89% is grown in China.
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Identification and Biology of CML Stem Cells
2016Chronic myeloid leukemia (CML) is a typical model to study cancer stem cell biology. CML stem cells reside in the CD34+CD38− fraction coexisting with normal hematopoietic stem cells (HSCs). By acquisition of BCR-ABL, an oncogenic fusion transcript encoding a constitutively active tyrosine kinase, HSCs become CML stem cells and progressively outgrow ...
Hiromi Iwasaki, Koichi Akashi
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Identification of phase separating proteins associated with human disease
Nature Reviews Molecular Cell Biology, 2023exaly
The Biology and Identification of Fungi
Allergy and Asthma Proceedings, 1982Ira F. Salkin, John H. Haines
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