Results 51 to 60 of about 232,747 (248)

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Intelligent Acousto‐Electrical Metamaterials (IAM) for Sound Source Detection

Advanced Materials, EarlyView.
Our proposed metamaterial concept enables sound source detection using a single material, in contrast to conventional arrays that require dozens or even hundreds of transducers. We show that the coupled acoustic–vibrational–electrical responses in piezoelectric metamaterials give rise to topology‐governed charge transport, producing distinct voltage ...
Victor Couëdel, Haotian Lu, Jiayan Zhang, Desheng Yao, Ananya Bhardwaj, Ramiro Contreras, Karim Sabra, Xiaoyu (Rayne) Zheng   +7 more
wiley   +1 more source

Time Series and Related Topics. In Memory of Ching-Zong Wei

, 2007
A major research area of Ching-Zong Wei (1949--2004) was time series models and their applications in econometrics and engineering, to which he made many important contributions. A conference on time series and related topics in memory of him was held on
Ho, Hwai-Chung, Ing, Ching-Kang, Lai, Tze Leung   +2 more
core   +1 more source

Tough, Ductile, and Strong Hard‐Soft Cementitious Composite Enabled by Multi‐Material Additive Manufacturing

Advanced Materials, EarlyView.
Drawing inspiration from the layered hard‐soft architecture found in sea sponges, this work establishes a new framework for architected cementitious composites (ACC) through multi‐material additive manufacturing (MMAM) process. The integration of mortar and elastomer phases into layered architectures enables synergistic toughening mechanisms, including
Aimane Najmeddine, Shashank Gupta, William Makinen, Zayvinn Lin, Krystal Delnoce, Reza Moini   +5 more
wiley   +1 more source

Triply‐Twinned Metamaterials: Unraveling the Mechanics and Failure Pathways Through High‐Resolution XCT

Advanced Materials, EarlyView.
Triply‐twinned architected lattices transform deformation from bending to stretching of struts, delivering up to threefold increases in stiffness and strength across polymeric and metallic systems. High‐resolution synchrotron XCT and image‐based simulations reveal how meta‐grain architecture, defects, and AM build orientation govern failure pathways ...
David McArthur, George Maddison, Jaianth Vijayakumar, Paul Tafforeau, Kathy Christofidou, Peter David Lee, PJ Tan, Chu Lun Alex Leung   +7 more
wiley   +1 more source

An Exponential Quantum Projection Filter for Open Quantum Systems

, 2018
An approximate exponential quantum projection filtering scheme is developed for a class of open quantum systems described by Hudson- Parthasarathy quantum stochastic differential equations, aiming to reduce the computational burden associated with online
Gao, Qing, Petersen, Ian R., Zhang, Guofeng   +2 more
core   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

Data-driven modelling of biological multi-scale processes

, 2015
Biological processes involve a variety of spatial and temporal scales. A holistic understanding of many biological processes therefore requires multi-scale models which capture the relevant properties on all these scales.
Hasenauer, Jan, Hross, Sabrina, Jagiella, Nick, Theis, Fabian J.   +3 more
core   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source