Results 91 to 100 of about 9,711,999 (311)

Blair Street house with Australian flag in window, New Norfolk [picture].

open access: yes, 1995
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892270 ...
Key, Mike, 1951-
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Pathological changes in the spleen of mice subjected to different time courses of restraint stress

open access: yesScientific Reports
The objective of this study was to investigate spleen pathology and immune cell subset alterations in mice exposed to acute and chronic restraint stress over various timeframes.
Lei Lei   +7 more
doaj   +1 more source

View from Peppermint Hill Lookout. View of Derwent River and New Norfolk town. Bush Inn in left foreground, St. Peters Church on right mid ground [picture].

open access: yes, 1995
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892270 ...
Key, Mike, 1951-
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Custom House, Esplanade, Launceston, view from the side [picture] /

open access: yes, 1995
Also available in an electronic version via the Internet at: http:// nla.gov.au/nla.pic-an11892262 ...
Key, Mike, 1951-
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The gut microbiota contributes to methamphetamine-induced reproductive toxicity in male mice

open access: yesEcotoxicology and Environmental Safety
Methamphetamine (METH) is a psychostimulant drug belonging to the amphetamine-type stimulant class, known to exert male reproductive toxicity. Recent studies suggest that METH can disrupt the gut microbiota.
Jia-Li Liu   +11 more
doaj   +1 more source

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