Results 121 to 130 of about 4,798,639 (300)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
An investigation of key growth industry sectors in Wales using Multi-Sectoral Qualitative Analysis [PDF]
This paper examines the problem of key sector identification in regional economies. Whilst the paper questions the desirability of policy focusing on the promotion of key sectors, it suggests that tools are generally underdeveloped to identify these ...
Calvin Jones, Jane Bryan, Max Munday
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A Statistical Model for the Identification of Key Sectors in I-O Models [PDF]
Following the seminal work by Bullard and Sebald [Effects of Parametric Uncertainty and Technological Change on In put-Out put Models, Rev. of Ec. And Stat., vol. 59,75-81], in this paper we present an innovative approach to sensitivity analysis in Input-
Marco Percoco
core
Zooplankton Identification Key
Uncover the hidden world of aquatic drifters with zooplankton identification keys, but beware the challenges that await curious researchers.
openaire +1 more source
Modifiable digital identification keys
, 2010 The Open Key Editor (OKE) is a tool for editing and enriching existing identification keys and to produce localized ‘minikeys’ that apply to local flora and fauna, such as in parks, nature reserves and school gardens, or keys that apply to a particular season.
van Spronsen E. +4 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Frontiers in ChemistryIntroductionThe similarity in appearance of poisonous and medicinal plants, such as Asarum heterotropoides (AH) and Cynanchum paniculatum (CP), poses safety risks due to frequent confusion.
Xin-Ru Zhang +10 more
doaj +1 more source