Results 181 to 190 of about 4,798,639 (300)

Revision of Entrophosporales, with Three Genera and an Identification Key for All Species Currently Attributed to This Order. [PDF]

J Fungi (Basel)
Silva GAD, Sieverding E, Assis DMA, Goto BT, Corazon-Guivin MA, Oehl F.   +5 more
europepmc   +1 more source

Notalina (Neonotalina) ralphi sp. nov. (Trichoptera, Leptoceridae), a new long-horned caddisfly from the Cerrado biome of Brazil, with new records for N. (Neonotalina) brasiliana Holzenthal, 1986 and an identification key. [PDF]

Zookeys, 2022
Silva Pereira E, Oliveira I, Desidério GR, Calor A, Hamada N.   +4 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Resolving issues in the genus Dioxys (Hymenoptera, Megachilidae, Dioxyini) in the West Palaearctic with a new identification key. [PDF]

Zookeys
Wood TJ.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The scorpions of the Estación de Biología Chamela, Jalisco, Mexico with the description of a new species of <i>Mesomexovis</i> (Scorpiones, Vaejovidae) and an identification key. [PDF]

Zookeys
de Araujo Lira AF, González-Santillán E.   +1 more
europepmc   +1 more source

Revision of the endemic Afrotropical genus Tetractenion (Hymenoptera, Ichneumonidae) with an identification key to genera of Banchinae for the region. [PDF]

Zookeys, 2020
Berry TR, van Noort S.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Taxonomic Diversity of <i>Ranunculus</i> Section <i>Ranunculastrum</i> (Ranunculaceae) in Tajikistan, With an Identification Key and a New Species Based in Part on Molecular Phylogenetic Evidence. [PDF]

Ecol Evol
Erst AS, Boboev MT, Boboev KM, Baasanmunkh S, Sharples MT, Kuznetsov AA, Kulikovskiy MS, Kostikova VA, Maltseva SY, Erst TV, Skaptsov MV, Xiang K, Lian L, Choi HJ, Wang W.   +14 more
europepmc   +1 more source

Identification key to the Anopheles mosquitoes of South America (Diptera: Culicidae). III. Male genitalia. [PDF]

Parasit Vectors, 2020
Sallum MAM, Obando RG, Carrejo N, Wilkerson RC.   +3 more
europepmc   +1 more source