A systematic review on global RSV genetic data: Identification of knowledge gaps. [PDF]
Rev Med Virol, 2022 Langedijk AC +8 more
europepmc +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Identification of knowledge translation theories, models or frameworks suitable for health technology reassessment: a survey of international experts. [PDF]
BMJ Open, 2021 Esmail R +4 more
europepmc +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Sewage Systems Surveillance for SARS-CoV-2: Identification of Knowledge Gaps, Emerging Threats, and Future Research Needs. [PDF]
Pathogens, 2021 Amereh F +6 more
europepmc +1 more source
The impact of visual cues and lexical knowledge on the perception of a non-native consonant contrast for Colombian adults [PDF]
, 2010 The study investigates the impact of visual cues and lexical knowledge on the identification of a nonnative phonemic contrast. Twenty native Colombians were tested on an identification task involving 16 minimal pairs of English words, produced by four ...
Hazan, V., Thompson, M.
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Critical Success Factors in Capturing Knowledge for Retention in IT-Supported Repositories
Information, 2014 In this paper, the authors demonstrate the suitability of IT-supported knowledge repositories for knowledge retention. Successful knowledge retention is dependent on what is stored in a repository and, hence, possible to share.
Lena Aggestam +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Identification of threats using linguistics-based knowledge extraction. [PDF]
, 2008 One of the challenges increasingly facing intelligence analysts, along with professionals in many other fields, is the vast amount of data which needs to be reviewed and converted into meaningful information, and ultimately into rational, wise decisions by policy makers. The advent of the world wide web (WWW) has magnified this challenge.
openaire +2 more sources