Results 71 to 80 of about 14,884,694 (278)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Science Mapping: A Systematic Review of the Literature

open access: yesJournal of Data and Information Science, 2017
Purpose We present a systematic review of the literature concerning major aspects of science mapping to serve two primary purposes: First, to demonstrate the use of a science mapping approach to perform the review so that researchers may apply the ...
Chaomei Chen
semanticscholar   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Rapid and pragmatic implementation mapping for pre-implementation contextual analysis in multisite implementation trials

open access: yesFrontiers in Health Services
BackgroundSystematic and data-driven implementation strategy selection is typically a resource-intensive process limited by time and implementation science expertise. Simultaneously, implementation trials often include externally driven timelines.
Laura Ellen Ashcraft   +9 more
doaj   +1 more source

[New Guinea, scale 1:63,360] [cartographic material] /

open access: yes, 1955
Provisional ed. Uncontoured (planimetric) map series of Papua New Guinea, compiled from aerial photography, showing minor roads, tracks, water features, buildings and populated places. Relief shown by spot heights.; Produced by National Mapping Office to
Australia. National Mapping Office.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

BED: a Biological Entity Dictionary based on a graph data model [version 3; referees: 2 approved]

open access: yesF1000Research, 2018
The understanding of molecular processes involved in a specific biological system can be significantly improved by combining and comparing different data sets and knowledge resources.
Patrice Godard, Jonathan van Eyll
doaj   +1 more source

Singapore 1:25,000 road map [cartographic material] /

open access: yes, 1980
Ed. 3 SMU. Shows selected buildings, points of interest, and schools.; Base information, aerial photography dated Jan. 1974, Aug. 1979 and partial ground verification up to Jan. 1980.; "R.S.O. metric grid."; Some sheets include insets.; Includes lists of
Singapore. Ministry of Defence. Mapping Unit.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Urandangi, Queensland [cartographic material] /

open access: yes, 1951
1st ed. Topographic map of Urandangi region, Queensland, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, windpumps, and bore, tank and well classifictions. Relief shown by hachures and spot heights.;
Australia. National Mapping Section.
core  

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