Results 91 to 100 of about 55,177 (246)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Precarity, Identity, and the Meaning of Cultural and Creative Work
AbstractThis chapter focuses on the subjective experiences of precarity as these were relayed to us and discussed during the research. In doing so, the chapter explores the significance of a number of existential themes relating to identity, vulnerability, and the desire for recognition that impacted on freelance and self-employed live performers ...
Philip Hancock, Melissa Tyler
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Handwriting as a means of Cultural Identity [PDF]
Journal of Forensic Sciences & Criminal Investigation, 2017 openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Cogent Arts & HumanitiesThe Makassar Kelong Performance (henceforth abbreviated as MKP) is an oral literary performance presented in the wedding tradition of the Makassar community to convey moral messages.
Nursalam Nursalam +5 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Mary Rack: Ethnic Distinctions, Local Meanings: Negotiating Cultural Identities in China
Tidsskriftet Antropologi, 2005 Anmeldes af Mikkel Bunkenborg
openaire +2 more sources