Results 171 to 180 of about 22,178 (297)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

The privacy preserving framework with virtual ring and identity-based cryptography for Smart Grid

open access: yes, 2019
One of the main challenges in the smart grid is how to efficiently manage the high-volume data from smart meters and sensors and preserve the privacy from the consumption data to avoid potential attacks (e.g., identity theft) for the involved prosumers ...
Sutanto, Leonard
core  

Distributed Lite CA Key Management Scheme in Mobile Ad Hoc Networks

open access: yes工程科学与技术, 2011
:In order to solve the problem of asymmetric key management in mobile ad hoc networks, a new distributed asymmetric key management scheme based on lite CA public key authentication framework and Shamir secret sharing scheme was presented.
doaj  

Text encryption through bio-inspired DNA and RNA sequencing. [PDF]

open access: yesPLoS One
Rashid OF, Abdulsahib SA, Al-Shahwani H.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Distributed Lite CA Key Management Scheme in Mobile Ad Hoc Networks

open access: yes工程科学与技术, 2012
:In order to solve the problem of asymmetric key management in mobile ad hoc networks, a new distributed asymmetric key management scheme based on lite CA public key authentication framework and Shamir secret sharing scheme was presented.
doaj  

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