Results 101 to 110 of about 1,637,583 (298)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Functional Identities

open access: yes, 2007
various constructions and concrete examples of d-free sets are given, and FIćs on d-free sets are thoroughly studied. Part III deals with applications. Its main purpose is to demonstrate how one can find FI's when considering different problems, and then effectively use the general theory exposed in Part II. Perhaps the most illuminating example of the
Brešar, Matej   +2 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Demystifying authenticity: Behavioral and neurophysiological signatures of self-positivity for authentic and presented selves

open access: yesNeuroImage
Authenticity has captivated scholars. But what is it? An emerging view considers it exaggerated favorability (self-enhancement), whereas traditional views regard it as self-accuracy and self-consistency.
Chengli Huang   +7 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Disturbing Femininity

open access: yesCulture Unbound: Journal of Current Cultural Research, 2013
When Helle Thorning-Schmidt in 2011 became the first female Prime Minister in Denmark, this “victory for the women” was praised in highly celebratory tones in Danish newspapers.
Kirsten Hvenegård-Lassen
doaj  

Medical care for transgender individuals at a hospital in southern Brazil: why do they drop out from our service?

open access: yesFrontiers in Public Health
ObjectiveThe objective of the study was to investigate dropout rates and discern potential factors contributing to the discontinuation of treatment provided to transgender individuals by the Transdisciplinary Gender Identity Program at the Hospital de ...
Fernanda Guadagnin   +10 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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