Results 51 to 60 of about 172,096 (252)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

What keeps them invested? Social identity and group formation in blockchain

Frontiers in Blockchain
Cryptocurrency technologies have spawned a vast network of millions of users. One notable aspect of crypto spaces is the emergence of vibrant communities that form around specific projects, with supporters gathering on interactive online platforms and ...
Annika Aebli, Fabienne Silberstein-Bamford, Fabienne Silberstein-Bamford, Joshua S. Bamford, Joshua S. Bamford, Joshua S. Bamford   +5 more
doaj   +1 more source

Reprogramming lineage identity through cell–cell fusion

Current Opinion in Genetics & Development, 2021
The conversion of differentiated cells to a pluripotent state through somatic cell nuclear transfer provided the first unequivocal evidence that differentiation was reversible. In more recent times, introducing a combination of key transcription factors into terminally differentiated mammalian cells was shown to drive their conversion to induced ...
Karen E, Brown, Amanda G, Fisher
openaire   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Using Artificial Intelligence Techniques to Implement a Multifactor Authentication System [PDF]

International Journal of Computational Intelligence Systems, 2011
The recent years have seen a rise in the number of cases of cyber-crime committed through identity theft and fraud. To address this problem, this paper uses adaptive neural-fuzzy inference system, fuzzy logic and artificial neural network to implement a ...
Jackson Phiri, Tie-Jun Zhao, Cong Hui Zhu, Jameson Mbale   +3 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Original article Readiness to deny group’s wrongdoing and willingness to fight for its members: the role of Poles’ identity fusion with the country and religious group

Current Issues in Personality Psychology, 2014
Background Identity fusion is a powerful visceral feeling of oneness with the group. Dozens of studies have demonstrated that identity fusion is a powerful predictor of endorsement of extreme behavior for the group.
Tomasz Besta, Ángel Gómez, Alexandra Vázquez   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Sense of safety or meaning in danger? Real-contact stick fighting as an imagistic ritual

Frontiers in Psychology
It is a common assumption that human behavior is guided by a desire to feel safe and avoid harm. However, this view is challenged by the popularity of high-risk leisure sport and other practices that involve subjecting oneself to a considerable danger ...
Teemu Pauha
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source