Results 81 to 90 of about 523,953 (261)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

What keeps them invested? Social identity and group formation in blockchain

Frontiers in Blockchain
Cryptocurrency technologies have spawned a vast network of millions of users. One notable aspect of crypto spaces is the emergence of vibrant communities that form around specific projects, with supporters gathering on interactive online platforms and ...
Annika Aebli, Fabienne Silberstein-Bamford, Fabienne Silberstein-Bamford, Joshua S. Bamford, Joshua S. Bamford, Joshua S. Bamford   +5 more
doaj   +1 more source

Perturbed Defects and T-Systems in Conformal Field Theory

, 2007
Defect lines in conformal field theory can be perturbed by chiral defect fields. If the unperturbed defects satisfy su(2)-type fusion rules, the operators associated to the perturbed defects are shown to obey functional relations known from the study of ...
Bachas C, Bachas C, Baxter R J, Di Francesco P, Dorey P, Dorey P, Dorey P Pillin M Pocklington A Runkel I Tateo R Watts G M T, Fateev V Zamolodchikov A B Zamolodchikov A B, Frenkel E, Friedan D, Fuchs J, Fuchs J Runkel I Schweigert C, Graham K, Graham K, Ingo Runkel, Kulish P P, Moore G W, Quella T, Teschner J, Teschner J, Zamolodchikov A B Zamolodchikov A B   +20 more
core   +3 more sources

Identity fusion: a systematic review

, 2020
Abstract The objective of the present investigation was to conduct a systematic review of empirical studies that have reported the use of identity fusion theory. The review followed guidelines and recommendations of the PRISMA statement. The following databases were used Web of Science, Scopus, ProQuest, ScienceDirect, Willey Online Library, EBSCO and ...
Henríquez, Diego, Urzúa, Alfonso, López-López, Wilson   +2 more
openaire   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Cognitive Linguistic Identity Fusion Score (CLIFS): A Scalable Cognition‐Informed Approach to Quantifying Identity Fusion from Text

Proceedings of the 2025 Conference on Empirical Methods in Natural Language Processing
Quantifying identity fusion -- the psychological merging of self with another entity or abstract target (e.g., a religious group, political party, ideology, value, brand, belief, etc.) -- is vital for understanding a wide range of group-based human behaviors.
Wright, Devin R., An, Jisun, Ahn, Yong-Yeol   +2 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

A pentagon of identities, graded tensor products and the Kirillov-Reshetikhin conjecture

, 2010
This paper provides a brief review of the relations between the Feigin-Loktev conjecture on the dimension of graded tensor products of $\g[t]$-modules, the Kirillov-Reshetikhin conjecture, the combinatorial ``M=N" conjecture, their proofs for all simple ...
Kedem, Rinat
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source