Results 101 to 110 of about 50,635 (295)

Perampanel as add‐on in high‐grade glioma–related epilepsy: Seizure control and QoL in a prospective, multicenter, real‐world 6‐month follow‐up study

Epilepsia Open, EarlyView.
Abstract Objective High‐grade astrocytomas, including glioblastomas, are aggressive brain tumors with poor prognosis and a 5‐year survival below 7%. Seizures affect up to 75% of glioma patients, especially in low‐grade tumors but also in high‐grade cases.
Matteo Impellizzeri, Paolo Paone, Giada Pauletto, Annacarmen Nilo, Simone Beretta, Andrea Salmaggi, Stefano Consoli, Stefano Quadri   +7 more
wiley   +1 more source

APROXIMACIÓN AL MÉTODO FILOSÓFICO Y LA CREACIÓN CONCEPTUAL

Astrolabio: Nueva Época, 2014
En el presente escrito me propongo mostrar cómo se producen los conceptos desde distintos enfoques filosóficos que encuentran, en ciertos puntos problemáticos y a pesar de sus diferencias irreductibles, zonas de contacto y convergencia entre sí.
Roque Farrán
doaj  

What if there were not secondary schools in city neighborhoods? Tensions between the improvement of schooling conditions and the defunding of some socio-educational inclusion policies in the Province of Córdoba

Education Policy Analysis Archives, 2019
This article presents a case study in a secondary school located in a City - Neighborhood of Córdoba Capital whose students are, predominantly, the first generation of families to access, stay, and graduate from secondary school.
Maria Cecilia Bocchio
doaj   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

Differentiation Syndrome and Sweet Syndrome‐Like Overlap Following Venetoclax–Azacytidine and G‐CSF Therapy

JEADV Clinical Practice, EarlyView.
ABSTRACT Differentiation syndrome (DS) and Sweet syndrome (SS) are inflammatory complications mediated by cytokine dysregulation, classically associated with therapies that promote myeloid differentiation or cytokine release. While DS has been primarily linked to all‐trans retinoic acid (ATRA) and IDH inhibitors, recent evidence suggests that ...
Katerina Grafanaki, Maria Gerbesi, Zoe Apalla, Dimitrios Tsokanas, Efstathia Pasmatzi, Alexandros Spyridonidis, Maria Liga   +6 more
wiley   +1 more source

Additional file 3: of Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities

, 2018
IDH1 mutant cells are better able to proliferate following radiation than IDH wildtype cells. A. Growth curve following radiation (0 and 10 Gy) shows average fold increases in cell number between IDH wildtype and IDH1 mutant groups over three passages ...
Joshua Breunig (5119277), Robert Prins (5119259), Albert Lai (73635), Ascia Eskin (253930), Rachelle Levy (5119274), Giovanni Coppola (46572), Matthew Garrett (2652571), Frank Pajonk (59951), Caius Radu (3400175), Jack Mottahedeh (5119268), Thomas Graeber (4218709), Jantzen Sperry (5119271), Kirsten Ludwig (5119265), Linda Liau (73631), Heather Christofk (3452684), Weihong Yan (2358406), Harley Kornblum (5119262), Daniel Braas (80410), Yue Qin (634751), Thuc Le (1344843)   +19 more
core   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Immune Heterogeneity of IDH Glioma Subtypes

, 2019
The metabolic gene isocitrate dehydrogenase 1 (IDH) gene is commonly mutated in WHO grade II and III gliomas and in a minority of WHO grade IV glioblastoma (GBM).
Richardson, Leland G.K.
core  

Potential Biomarkers for IDH-Mutant and IDH-Wild-Type Glioblastomas: A Single-Center Retrospective Study

Background/Objectives: Glioblastoma ranks among the most aggressive brain tumors, with poor prognosis. Currently, there are insufficient data regarding the prognostic value of isocitrate dehydrogenase (IDH) mutation status and inflammatory markers.
Mustafa Emre Sarac, Zeki Boga, Semih Kivanc Olguner, Tolga Akbıyık, Ahmet Hamit Çınkı, Ümit Kara   +5 more
core   +1 more source