Results 251 to 260 of about 50,635 (295)

Golden rules for optimizing the diagnostic pathway of IDH-mutant tumors: bridging evidence and clinical practice in cholangiocarcinoma and adult-type diffuse gliomas. [PDF]

Pathologica
Antonelli M, Barresi V, Bertero L, Daniele B, Fassan M, Malapelle U, Normanno N, Pruneri G, Scarpa A.   +8 more
europepmc   +1 more source

A Case of IDH-Mutant Astrocytoma Harboring an IDH2 R172_H173delinsSN Variant. [PDF]

Neuropathology
Auen T, Chen J, Shonka N, Cathcart S.
europepmc   +1 more source

Mutacije IDH

openaire   +1 more source

Oral Presentation

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

ePoster

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

ePosters Virtual

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

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Characteristics of IDH-mutant gliomas with non-canonical IDH mutation

Journal of Neuro-Oncology, 2020
Approximately 10% of IDH-mutant gliomas harbour non-canonical IDH mutations (non-p.R132H IDH1 and IDH2 mutations).The aim of this study was to analyse the characteristics of non-canonical IDH-mutant gliomas.We retrospectively analysed the characteristics of 166 patients with non-canonical IDH mutant gliomas and compared them to those of 155 consecutive
Charlotte Brönnimann, R Seizeur, G Gauchotte   +2 more
exaly   +3 more sources

Biology of IDH mutant cholangiocarcinoma

Hepatology, 2022
Abstract Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are the most frequently mutated metabolic genes across human cancers. These hotspot gain‐of‐function mutations cause the IDH enzyme to aberrantly generate high levels of the oncometabolite, R‐2‐hydroxyglutarate, which competitively inhibits enzymes that regulate epigenetics, DNA repair,
Meng‐Ju Wu, Lei Shi, Joshua Merritt, Andrew X. Zhu, Nabeel Bardeesy   +4 more
openaire   +2 more sources

IDH-mutant brainstem glioma

Voprosy neirokhirurgii imeni N.N. Burdenko, 2022
Diffuse midline gliomas are relatively rare in adults. Regardless of age, all diffuse midline gliomas are routinely examined in our Center for the presence of the H3F3A K27M gene mutation. However, we identified IDH-mutant brainstem glioma in a 42-year-old man for the first time.
M.V. Ryzhova, S.A. Galstyan, E.N. Telysheva, D.I. Pitskhelauri, A.V. Kosyrkova, Ya.A. Latyshev   +5 more
openaire   +2 more sources