Results 291 to 300 of about 154,739 (326)

Supplementary Table S9 from <i>(R)</i>-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in <i>IDH</i>-Mutant Cancers

Kathryn Gunn, Matti Myllykoski, John Z. Cao, Manna Ahmed, Bofu Huang, Betty Rouaisnel, Bill H. Diplas, Michael M. Levitt, Ryan Looper, John G. Doench, Keith L. Ligon, Harley I. Kornblum, Samuel K. McBrayer, Hai Yan, Cihangir Duy, Lucy A. Godley, Peppi Koivunen, Julie-Aurore Losman   +17 more
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Intraoperative Spectroscopic and Mass Spectrometric Assessment of Glioma Margins: A Systematic Review and Meta-Analysis. [PDF]

Cancers (Basel)
Tykocki T, Rakasz Ł.
europepmc   +1 more source

Temporal muscle measurements as predictor for outcome in a cohort of IDH-wildtype glioblastoma patients. [PDF]

Brain Spine
Pinson H, De Rudder C, De Backer L, Van Sinay A, Boterberg T, Hallaert G.   +5 more
europepmc   +1 more source

Table 2_Nontargeted metabolomics uncovering metabolite signatures in glioblastoma: a preliminary study on candidate biomarker discovery for IDH subtyping and survival prediction.docx

Peng Xu (17962), Xiling Chen (1412686), Qun Li (222962), Zheqing Dong (21265436), Ji Zhu (106734), Zhipeng Su (718338), Qifan Zhang (3856051), Kui Fang (15295312)   +7 more
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Astrocytoma, IDH-mutant - grade 4

, 2016
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Mutacije IDH

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Biology of IDH mutant cholangiocarcinoma

Hepatology, 2022
Abstract Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are the most frequently mutated metabolic genes across human cancers. These hotspot gain‐of‐function mutations cause the IDH enzyme to aberrantly generate high levels of the oncometabolite, R‐2‐hydroxyglutarate, which competitively inhibits enzymes that regulate epigenetics, DNA repair,
Meng‐Ju Wu, Lei Shi, Joshua Merritt, Andrew X. Zhu, Nabeel Bardeesy   +4 more
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