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IEEE Transactions on Medical Imaging, 2022
The accurate prediction of isocitrate dehydrogenase (IDH) mutation and glioma segmentation are important tasks for computer-aided diagnosis using preoperative multimodal magnetic resonance imaging (MRI).
Jianhong Cheng +3 more
semanticscholar +1 more source
The accurate prediction of isocitrate dehydrogenase (IDH) mutation and glioma segmentation are important tasks for computer-aided diagnosis using preoperative multimodal magnetic resonance imaging (MRI).
Jianhong Cheng +3 more
semanticscholar +1 more source
Voprosy neirokhirurgii imeni N.N. Burdenko, 2022
Diffuse midline gliomas are relatively rare in adults. Regardless of age, all diffuse midline gliomas are routinely examined in our Center for the presence of the H3F3A K27M gene mutation. However, we identified IDH-mutant brainstem glioma in a 42-year-old man for the first time.
M.V. Ryzhova +5 more
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Diffuse midline gliomas are relatively rare in adults. Regardless of age, all diffuse midline gliomas are routinely examined in our Center for the presence of the H3F3A K27M gene mutation. However, we identified IDH-mutant brainstem glioma in a 42-year-old man for the first time.
M.V. Ryzhova +5 more
openaire +2 more sources
No shinkei geka. Neurological surgery, 2023
The 5th edition of the WHO Classification of Central Nervous System Tumours(WHO2021)emphasizes the importance of molecular classification. A significant update was that glioblastoma IDH-mutant from WHO2016 was renamed and classified as astrocytoma IDH-mutant WHO grade 4 in WHO2021.
Ichiyo, Shibahara, Toshihiro, Kumabe
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The 5th edition of the WHO Classification of Central Nervous System Tumours(WHO2021)emphasizes the importance of molecular classification. A significant update was that glioblastoma IDH-mutant from WHO2016 was renamed and classified as astrocytoma IDH-mutant WHO grade 4 in WHO2021.
Ichiyo, Shibahara, Toshihiro, Kumabe
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Characteristics of IDH-mutant gliomas with non-canonical IDH mutation
Journal of Neuro-Oncology, 2020Approximately 10% of IDH-mutant gliomas harbour non-canonical IDH mutations (non-p.R132H IDH1 and IDH2 mutations).The aim of this study was to analyse the characteristics of non-canonical IDH-mutant gliomas.We retrospectively analysed the characteristics of 166 patients with non-canonical IDH mutant gliomas and compared them to those of 155 consecutive
Poetsch, L. +12 more
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Multi-Level Feature Exploration and Fusion Network for Prediction of IDH Status in Gliomas From MRI
IEEE journal of biomedical and health informatics, 2023Isocitrate dehydrogenase (IDH) is one of the most important genotypes in patients with glioma because it can affect treatment planning. Machine learning-based methods have been widely used for prediction of IDH status (denoted as IDH prediction). However,
Jiawei Zhang +5 more
semanticscholar +1 more source
Neuro-Oncology
BACKGROUND This study evaluated whether generative artificial intelligence-based augmentation (GAA) can provide diverse and realistic imaging phenotypes and improve deep learning-based classification of isocitrate dehydrogenase (IDH) type in glioma ...
Hye Hyeon Moon +9 more
semanticscholar +1 more source
BACKGROUND This study evaluated whether generative artificial intelligence-based augmentation (GAA) can provide diverse and realistic imaging phenotypes and improve deep learning-based classification of isocitrate dehydrogenase (IDH) type in glioma ...
Hye Hyeon Moon +9 more
semanticscholar +1 more source
Abstract The 2021 World Health Organization (WHO) classification defines glioblastoma as a malignant tumor of neuroglial or astroglial origin that lacks mutations in the isocitrate dehydrogenase (IDH) 1 or 2 genes. The new definition of glioblastoma also includes IDH-wildtype tumors without histological features of WHO grade 4 if one of ...
Michael Weller +4 more
+4 more sources
Michael Weller +4 more
+4 more sources
No shinkei geka. Neurological surgery
Abstract Astrocytoma, isocitrate dehydrogenase (IDH)-mutant is diagnosed by the presence of an IDH mutation and no 1p/19q codeletion, usually with loss of ATRX expression. Based on histological criteria three grades are distinguished, the presence of homozygous deletion of the CDKN2A gene in the updated results in the World Health ...
Martin J. van den Bent +3 more
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Abstract Astrocytoma, isocitrate dehydrogenase (IDH)-mutant is diagnosed by the presence of an IDH mutation and no 1p/19q codeletion, usually with loss of ATRX expression. Based on histological criteria three grades are distinguished, the presence of homozygous deletion of the CDKN2A gene in the updated results in the World Health ...
Martin J. van den Bent +3 more
openaire +3 more sources
The implications of IDH mutations for cancer development and therapy
Nature Reviews Clinical Oncology, 2021Christopher J. Pirozzi, Hai Yan
semanticscholar +1 more source