Results 91 to 100 of about 35,587 (246)

Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature

Histopathology, EarlyView.
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Costantino Ricci, Dario de Biase, Thais Maloberti, Agnese Orsatti, Thomas M Ulbright, Muhammad T Idrees, Esther Oliva, Kristine Cornejo, João Lobo, Kvetoslava Michalova, Maria Rosaria Raspollini, Sean R Williamson, Geert JLH van Leenders, Chia‐Sui Kao, Fiona Maclean, Ankur R Sangoi, Adeboye O Osunkoya, Michelangelo Fiorentino, Antonio De Leo, Giovanni Tallini, Andres Martin Acosta   +20 more
wiley   +1 more source

The Potential Effect of the IDH1 Mutation and MGMT Gene Promoter Methylation on the Control of Glioblastoma-Associated Epilepsy in Patients Receiving Anti-Epileptic Agents and Chemotherapies

, 2021
Maher Kurdi
openalex   +1 more source

Mutational status of IDH1 in uveal melanoma

Experimental and Molecular Pathology, 2016
Uveal (intraocular) melanoma is an uncommon malignancy that comprises a small percentage of all melanoma cases. While many uveal melanomas harbor mutations in the BRCA-Associated Protein 1 (BAP1) gene, the genetics of non-BAP1 associated tumors are not completely understood.
Patrick J. Cimino, Yungtai Kung, Joshua I. Warrick, Shu-Hong Chang, C. Dirk Keene   +4 more
openaire   +2 more sources

Prediction of Postoperative Intravesical Recurrence Using Urine DNA Monitoring in Nonmuscular‐Invasive Urothelial Bladder Cancer

International Journal of Urology, EarlyView.
ABSTRACT Objectives Considering the high frequency of intravesical recurrence in bladder urothelial carcinoma (UBC), accurate non‐invasive biomarkers for recurrence prediction are needed for better management after transurethral surgery. This pilot study examined the usefulness of urine DNA for detecting and predicting intravesical recurrence in UBC ...
Masashi Shiozaki, Tomonori Minagawa, Hitoshi Yokoyama, Yosuke Hirotsu, Toshio Oyama, Masao Omata, Yoshiyuki Akiyama   +6 more
wiley   +1 more source

Molecular Alterations in Osteosarcomas of the Oral and Maxillofacial Region: A Scoping Review

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Given the rarity and aggressive nature of osteosarcomas (OS) in the oral and maxillofacial region, understanding their molecular alterations is essential to improve diagnosis, prognosis, and guide targeted therapies. This study aimed to map molecular alterations associated with oral and maxillofacial OS, providing an overview of the
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Moisés Willian Aparecido Gonçalves, Carlos Takahiro Chone, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +6 more
wiley   +1 more source

Metabolic reprogramming in mutant IDH1 glioma cells.

PLoS ONE, 2015
BackgroundMutations in isocitrate dehydrogenase (IDH) 1 have been reported in over 70% of low-grade gliomas and secondary glioblastomas. IDH1 is the enzyme that catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate while mutant IDH1 ...
Jose L Izquierdo-Garcia, Pavithra Viswanath, Pia Eriksson, Myriam M Chaumeil, Russell O Pieper, Joanna J Phillips, Sabrina M Ronen   +6 more
doaj   +1 more source

Epidemiology and characteristics of validated mixed phenotype acute leukaemia—A comprehensive nationwide Danish cohort study

British Journal of Haematology, EarlyView.
Lisa‐Maj Christensen, Daniel Tuyet Kristensen, Karen Dybkær, Kirsten Grønbæk, Tarec Christoffer El‐Galaly, Marianne Schmidt Ettrup, Jonas Faartoft Jensen, Hans Beier Ommen, Anne Louise Tølbøll Sørensen, Dennis Lund Hansen, Rasmus Froberg Brøndum, Marianne Tang Severinsen   +11 more
wiley   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

Abundance of d‐2‐hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1‐expressing cells [PDF]

, 2019
Balabhaskararao Kancharana, Kumar Katragunta, Uma Maheswara Sarma, Nishant Jain   +3 more
openalex   +1 more source

Malignant Potential of Thyroid Follicular Nodular Disease With Solid/Trabecular Components: A Case Report

Pathology International, EarlyView.
A case of noninvasive thyroid follicular nodular disease (TFND) with a solid/trabecular (ST) components (STc) developed skin implantation and lung metastases 3 years after lobectomy. The skin tumor resembled STc of the primary TFND and harbored EZH1, KRAS and TERT promoter mutations.
Mayu Ueda, Katsuya Matsuda, Yusuke Mori, Hirokazu Kurohama, Hiroyuki Mishima, Koh‐Ichiro Yoshiura, Norisato Mitsutake, Hisakazu Shindo, Shinya Sato, Hiroyuki Yamashita, Atsushi Kawakami, Masahiro Nakashima   +11 more
wiley   +1 more source