Results 111 to 120 of about 34,512 (245)
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
Photochemistry and Photobiology, EarlyView.The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal +3 more
wiley +1 more source
IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming
eLifeIsocitrate dehydrogenase 1 (IDH1) is the key enzyme that can modulate cellular metabolism, epigenetic modification, and redox homeostasis. Gain-of-function mutations and decreased expression of IDH1 have been demonstrated to be associated with ...
Mengjia Li +11 more
doaj +1 more source
IDH1 mutant structures reveal a mechanism of dominant inhibition [PDF]
, 2010 Shimin Zhao, Kun‐Liang Guan
openalex +1 more source
Pathology International, EarlyView.A case of noninvasive thyroid follicular nodular disease (TFND) with a solid/trabecular (ST) components (STc) developed skin implantation and lung metastases 3 years after lobectomy. The skin tumor resembled STc of the primary TFND and harbored EZH1, KRAS and TERT promoter mutations.
Mayu Ueda +11 more
wiley +1 more source
IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis [PDF]
, 2010 Felicitas Thol +13 more
openalex +1 more source
International Journal of Cancer, Volume 157, Issue 10, Page 2156-2172, 15 November 2025.What's New? The anti‐aging protein klotho (KL) is a potential tumor suppressor and prognostic marker in glioblastoma. Little is known, however, about its mechanism of action and clinical relevance. This study examined KL expression in the setting of persistent inflammation and other stressors, including radiotherapy.
Andrea Galluzzo +19 more
wiley +1 more source
Mutant IDH1 Confers an in Vivo Growth in a Melanoma Cell Line with BRAF Mutation [PDF]
, 2011 Tatsuhiro Shibata +4 more
openalex +1 more source
Intraventricular mass in a 49‐year‐old male
Brain Pathology, EarlyView.
Connor R. Zuraski +3 more
wiley +1 more source
Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism
International Journal of Cancer, Volume 157, Issue 10, Page 1991-2003, 15 November 2025.Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello +7 more
wiley +1 more source
2‐Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size [PDF]
, 2011 David Capper +7 more
openalex +1 more source