Results 151 to 160 of about 34,512 (245)

Serum Proteomic Profile Based on the TGF‐β Pathway Stratifies Risk of Hepatocellular Carcinoma

Liver International, Volume 45, Issue 10, October 2025.
ABSTRACT Background Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related deaths, primarily due to late‐stage diagnosis. In this multicenter study, our goal is to identify functional biomarkers that stratify the risk of HCC in patients with cirrhosis (CP) for early diagnosis.
Xiyan Xiang, Kirti Shetty, Herbert Yu, Bibhuti Mishra, Linda L. Wong, Xianghong Jasmine Zhou, Sanjaya K. Satapathy, James M. Crawford, Patricia S. Latham, Steven‐Huy Han, Brandon Mathew, Nabil N. Dagher, Lawrence Lau, Fellanza Cacaj, Anil K. Vegesna, Srinivasan Dasarathy, Aiwu R. He, Hai Huang, Richard L. Amdur, Lopa Mishra   +19 more
wiley   +1 more source

Diagnostic and prognostic value of IDH1 mutation in gliomas

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To discuss the significance of IDH1 mutation for diagnosis and prognosis of gliomas through detecting of IDH1 mutation in supratentorial glioma cells.
Yan⁃wu YANG, Fei XIE, Jun⁃jia TANG, Shuang LIU, Xiang WANG, Yan⁃hui LIU, Qing MAO   +6 more
doaj  

Faculty Opinions recommendation of Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

, 2011
Robert Abraham
openalex   +2 more sources

Can Diffusion Tensor Imaging Noninvasively Detect IDH1 Gene Mutations in Astrogliomas? A Retrospective Study of 112 Cases [PDF]

, 2014
Wenli Tan, Weiyuan Huang, Bo Yin, Ji Xiong, Jinsong Wu, Daoying Geng   +5 more
openalex   +1 more source

Use of DNA Methylation Profiling as a Molecular Classification Tool for Paediatric Central Nervous System Tumours: A Middle‐Income Country Population–Based Study

Neuropathology and Applied Neurobiology, Volume 51, Issue 5, October 2025.
ABSTRACT Paediatric central nervous system (CNS) tumours are the second most common childhood malignancy and the leading cause of cancer‐related mortality in this age group. Histopathological diagnosis can be challenging, particularly for rare or ambiguous tumours, and may result in misclassification.
Mayara F. Euzébio, Felipe L. T. Silva, Iva L. Hoffmann, Juliana S. Ruas, Larissa Akemi Kido, Dieila G. de Lima, Luciano Queiroz, Izilda A. Cardinalli, Ana Luiza Seidinger, Suelen Nascimento, Helder Tedeschi, Renato D. Puga, Priscila Pini Zenatti Sales, Patricia Y. Jotta, Mariana Maschietto   +14 more
wiley   +1 more source

IDH1 Mutations in Oligodendroglial Tumors: Comparative Analysis of Direct Sequencing, Pyrosequencing, Immunohistochemistry, Nested PCR and PNA‐Mediated Clamping PCR

, 2012
Dakeun Lee, Yeon‐Lim Suh, So Young Kang, Tae In Park, Ji Yun Jeong, Se Hoon Kim   +5 more
openalex   +2 more sources

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity [PDF]

, 2014
Suganthi Chittaranjan, Susanna Chan, C. Paul Yang, Kevin Yang, Vincent Chen, Annie Moradian, Marlo Firme, Jungeun Song, Nancy E. Go, Michael Blough, Jennifer A. Chan, J. Gregory Cairncross, Sharon M. Gorski, Gregg B. Morin, Stephen Yip, Marco A. Marra   +15 more
openalex   +1 more source

The AhR Is a Critical Regulator of the Pulmonary Response to Cannabis Smoke

The FASEB Journal, Volume 39, Issue 18, 30 September 2025.
AhR activation coordinates the pulmonary response to cannabis smoke. Inhalation of cannabis smoke disrupts epithelial integrity and promotes inflammation. AhR is activated by cannabis smoke and regulates cytoskeletal structure, detoxification, antioxidant, and immune pathways.
Emily T. Wilson, Roham Gorgani, Nicole S. Heimbach, Alexandra Bartolomucci, Thupten Tsering, Julia V. Burnier, David H. Eidelman, Carolyn J. Baglole   +7 more
wiley   +1 more source

IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

, 2012
Masato Sasaki, Christiane B. Knobbe‐Thomsen, Joshua Munger, Evan Lind, Dirk Brenner, Anne Brüstle, Isaac S. Harris, Roxanne Holmes, Andrew Wakeham, Jillian Haight, Annick You-Ten, Wanda Y. Li, Stefanie S. Schalm, Shinsan M. Su, Carl Virtanen, Guido Reifenberger, Pamela S. Ohashi, Dwayne L. Barber, María E. Figueroa, Ari Melnick, Juan Carlos Zúñiga‐Pflücker, Tak W. Mak   +21 more
openalex   +2 more sources

METABOLIC IMAGING BIOMARKERS FOR MUTANT IDH1 GLIOMAS [PDF]

, 2014
Sabrina M. Ronen, José Luis Izquierdo-García, Myriam M. Chaumeil, Larry Cai, Joanna J. Phillips, Russell O. Pieper   +5 more
openalex   +1 more source