Results 181 to 190 of about 58,205 (308)
Supplementary Data #2 from Genomic Profiling Identifies Association of <i>IDH1/IDH2</i> Mutation with Longer Relapse-Free and Metastasis-Free Survival in High-Grade Chondrosarcoma
, 2023 Guo Zhu, Khédoudja Nafa, Narasimhan P. Agaram, Ahmet Zehir, Ryma Benayed, Justyna Sadowska, Laetitia Borsu, Ciara M. Kelly, William D. Tap, Nicola Fabbri, Edward A. Athanasian, Patrick J. Boland, John H. Healey, Michael F. Berger, Marc Ladanyi, Meera Hameed +15 moreopenalex +1 more sourceSynthetic lethality in cancer therapy: Mechanisms, models and clinical translation for overcoming therapeutic resistance
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale
Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...Junyan Li, Liyuan Zhang, Yan Shang, Juan Liu, Hailong Zhao +4 morewiley +1 more sourceSupplementary Figure S5 from Radioprotection of <i>IDH1</i>-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
, 2023 Remco J. Molenaar, Dennis Botman, Myrthe A. Smits, Vashendriya V. Hira, Sanne A. van Lith, Jan Stap, Peter Henneman, Mohammed Khurshed, Krissie Lenting, Adri N. Mul, Dionysia Dimitrakopoulou, Cornelis M. van Drunen, Ron A. Hoebe, Tomas Radivoyevitch, Johanna W. Wilmink, Jaroslaw P. Maciejewski, W. Peter Vandertop, William P. J. Leenders, Fonnet E. Bleeker, Cornelis J.F. Van Noorden +19 moreopenalex +1 more sourceSupplementary Figure S3 from Radioprotection of <i>IDH1</i>-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
, 2023 Remco J. Molenaar, Dennis Botman, Myrthe A. Smits, Vashendriya V. Hira, Sanne A. van Lith, Jan Stap, Peter Henneman, Mohammed Khurshed, Krissie Lenting, Adri N. Mul, Dionysia Dimitrakopoulou, Cornelis M. van Drunen, Ron A. Hoebe, Tomas Radivoyevitch, Johanna W. Wilmink, Jaroslaw P. Maciejewski, W. Peter Vandertop, William P. J. Leenders, Fonnet E. Bleeker, Cornelis J.F. Van Noorden +19 moreopenalex +1 more sourceUnveiling relative lymphopenia and elevated monocyte‐to‐lymphocyte count as novel independent adverse prognostic factors in chronic myelomonocytic leukemia (CMML)—Proposal of the objective prognostic index for CMML (OPIC)
HemaSphere, Volume 10, Issue 1, January 2026.Abstract
Chronic myelomonocytic leukemia (CMML) shows marked prognostic heterogeneity. Although leukocytosis is a recognized adverse prognostic factor, the contribution of its individual components remains insufficiently defined. In a cohort of 240 patients classified according to International Consensus Classification (ICC) and World Health ...Xavier Calvo, Abora Rial‐Villavecchia, David Roman‐Bravo, Sara Garcia‐Avila, Lucia Gomez‐Perez, Marta Salido, Anna Puiggros, Blanca Espinet, Concepcion Fernandez‐Rodriguez, Barbara Tazon‐Vega, Beatriz Bellosillo, Sandra Castaño‐Díez, Marina Díaz‐Beyá, Jordi Esteve, Carmen Lome, Lluis Colomo, Lourdes Florensa, Ana Ferrer del Álamo, Juan Jose Rodriguez‐Sevilla, Leonor Arenillas +19 morewiley +1 more sourceSupplementary Figures from Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells
, 2023 Mahsa Zarei, Shruti Lal, Seth J. Parker, Avinoam Nevler, Ali Vaziri‐Gohar, Katerina Dukleska, Nicole C. Mambelli‐Lisboa, Cynthia Moffat, Fernando F. Blanco, Saswati N. Chand, Masaya Jimbo, Joseph A. Cozzitorto, Wei Jiang, Charles J. Yeo, Eric Londin, Erin L. Seifert, Christian M. Metallo, Jonathan R. Brody, Jordan M. Winter +18 moreopenalex +1 more source