Results 51 to 60 of about 4,884 (208)

Frequency of Rare Allelic Variation in Candidate Genes among Individuals with Low and High Urinary Calcium Excretion [PDF]

, 2013
Our study investigated the association of rare allelic variants with extremes of 24-hour urinary calcium excretion because higher urinary calcium excretion is a dominant risk factor for calcium-based kidney stone formation.
Curhan, Gary C., Genovese, Giulio, Mount, David B., Pollak, Martin R., Toka, Hakan R.   +4 more
core   +3 more sources

Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies

Andrology, Volume 13, Issue 5, Page 1044-1064, July 2025.
Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi, Maëva Drouault, Joao C. Ribeiro, Violaine Simon, Marjorie Whitfield, Aminata Touré   +5 more
wiley   +1 more source

Hydrochlorothiazide in CLDN16 mutation [PDF]

, 2017
Background. Hydrochlorothiazide (HCT) is applied in the therapy of familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) caused by claudin-16 (CLDN16) mutation. However, the short-term efficacy of HCT to reduce hypercalciuria in FHHNC
Dötsch, Jörg, Gravou-Apostolatou, Chara, Konrad, Martin, Plank, Christian, Rascher, Wolfgang, Stöhr, Wolfgang, Zimmermann, Bettina   +6 more
core  

Silicosarcoidosis: Histologic and Clinical Features of an Occupational Granulomatous Disease

American Journal of Industrial Medicine, Volume 68, Issue 6, Page 491-507, June 2025.
ABSTRACT Sarcoidosis is a multisystem inflammatory disease of unknown etiology. Growing evidence indicates that occupational exposure to respirable crystalline silica (RCS) is associated with an increased incidence of sarcoidosis. Yet a diagnosis of sarcoidosis rarely prompts investigation to identify preventable exposures.
Jeremy T. Hua, Carlyne D. Cool, Einat Fireman Klein, Yochai Adir, Lukas J. Lee, Lauren M. Zell‐Baran, Robert A. Cohen, Richard C. Kraus, E. Brigitte Gottschall, Silpa D. Krefft, Charles Van Hook, Cecile S. Rose   +11 more
wiley   +1 more source

Pharmacological interventions for preventing complications in patients with idiopathic hypercalciuria: A systematic review

Nefrología (English Edition), 2022
Objective: To assess the effects of pharmacological interventions in patients with idiopathic hypercalciuria. Methods: We performed a search of multiple databases, trial registries, grey literature and conference proceedings up to October 2019.
Natalia Ferre, Ester Parada, Albert Balaguer, Albert Feliu, Marta Roqué-Figuls, Juan Victor A. Franco, Joaquín Escribano   +6 more
doaj   +1 more source

‘Bone Health—Across a Woman's Lifespan’

Clinical Endocrinology, Volume 102, Issue 4, Page 389-402, April 2025.
ABSTRACT Despite a high burden of osteoporosis and minimal trauma fractures worldwide, there is still a treatment gap in timely diagnosis and optimal treatment. There is also a lack of international consensus and guidelines on the management of bone fragility in premenopausal women.
Gabrielle Stokes, Madhuni Herath, Navira Samad, Anne Trinh, Frances Milat   +4 more
wiley   +1 more source

Idiopathic hypercalciuria [PDF]

Journal of the American Society of Nephrology, 1994
The original contributions of Jacob Lemann to mineral metabolism, especially calcium metabolism and idopathic hypercalciuria, are reviewed. One group of studies concern acid base balance and calcium loss, showing that acid loads increase calcium loss in the urine. Another group of studies concern the calciuria of glucose or carbohydrate ingestion, with
F L, Coe, J H, Parks
openaire   +2 more sources

Role of the calcium‐sensing receptor in regulating vascular function

Journal of Cell Communication and Signaling, Volume 19, Issue 1, March 2025.
Representation of the role of the CaSR in the vasculature shows that a rise in extracellular Ca2+ concentration ([Ca2+]o) stimulates the CaSR expressed at the plasma membrane of perivascular sensory nerves, VECs, and VSMCs, which leads to the release of vasodilator substances (e.g., calcitonin‐related gene‐related peptide (CGRP), substance P (Sub P ...
Anthony P. Albert, Harry Z.E. Greenberg
wiley   +1 more source

Idiopathic Hypercalciuria in Children With Vesico Ureteral Reflux and Recurrent Urinary Tract Infection

Urology Journal, 2010
Purpose: Our aim was to determine association of vesicoureteral reflux (VUR) and idiopathic hypercalciuria in children with recurrent and single episode of urinary tract infection (UTI).Materials and Methods: The study group consisted of 45 children with
Hashem Mahmoodzadeh
doaj  

Phosphoinositide Metabolism: Biochemistry, Physiology and Genetic Disorders

Journal of Inherited Metabolic Disease, Volume 48, Issue 2, March 2025.
ABSTRACT Phosphatidylinositol, a glycerophospholipid with a myo‐inositol head group, can form seven different phosphoinositides (PItds) by phosphorylation at inositol carbons 3, 4 and/or 5. Over 50 kinases and phosphatases participate in PItd metabolism, creating an interconnected PItd network that allows for precise temporal and spatial regulation of ...
Francis Rossignol, Foudil Lamari, Grant A. Mitchell   +2 more
wiley   +1 more source