Results 91 to 100 of about 12,579 (209)

Necrotizing autoimmune myopathy: Clinicopathologic study from a single tertiary care centre

Annals of Indian Academy of Neurology, 2018
Background: Idiopathic inflammatory myopathies (IIMs) are a group of chronic, autoimmune disorders which include a new entity, necrotizing autoimmune myopathy (NAM). NAM lacks inflammation and presents with markedly elevated creatinine phosphokinase (CPK)
Sobiya Mahnaz Ayesha, A K Meena, Navatha Vangala, Liza Rajasekhar, Subhash Kaul, Rupam Borgahain, Megha S Uppin   +6 more
doaj   +1 more source

Plasma levels of adhesion molecules are elevated in dermatomyositis-interstitial lung disease and associated with low paraoxonase-1 activity

Arthritis Research & Therapy
Objective To evaluate circulating levels of intercellular cell adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) in patients with dermatomyositis (DM) and DM associated interstitial lung disease (DM-ILD).
Sangmee Sharon Bae, Ani Shahbazian, Jennifer Wang, Daniela Markovic, Tiffany De Leon, Yuna Lee, Srinivasa T. Reddy, Christina Charles-Schoeman   +7 more
doaj   +1 more source

Update on idiopathic inflammatory myopathies.

Autoimmunity, 2006
The inflammatory myopathies are a group of acquired diseases, characterized by an inflammatory infiltrate of the skeletal muscle. On the basis of clinical, immuno-pathological and demographic features, three major diseases can be identified: dermatomyositis (DM); polymyositis (PM); and inclusion body myositis (IBM).
BRIANI, CHIARA, DORIA, ANDREA, SARZI PUTTINI P, DALAKAS MC   +3 more
openaire   +2 more sources

Treatment of idiopathic inflammatory myopathies

Joint Bone Spine
Adult idiopathic inflammatory myopathies (IIMs) are rare autoimmune disorders affecting multiple organs, making diagnosis and treatment challenging. Current management relies on immunosuppressants like corticosteroids, methotrexate, azathioprine, mycophenolate mofetil, rituximab, and intravenous immunoglobulin, though treatment responses vary across ...
Raquel Campanilho-Marques, João Eurico Fonseca, Pedro M. Machado   +2 more
openaire   +2 more sources

Anti-HMGCR myopathy: a first case report from North Africa and literature insights

Frontiers in Immunology
Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy is a rare idiopathic inflammatory myopathy characterized by severe muscle damage and minimal extra-muscular involvement.
Houssem Abida, Houssem Abida, Imen Zamali, Imen Zamali, Imen Zamali, Imène Rachdi, Imène Rachdi, Zakaria Saied, Zakaria Saied, Ahlem Ben Hmid, Ahlem Ben Hmid, Ahlem Ben Hmid, Samar Samoud, Samar Samoud, Yousr Galai, Fatma Daoud, Fatma Daoud, Fatma Boussema, Fatma Boussema, Samia Ben Sassi, Samia Ben Sassi, Zohra Aydi, Zohra Aydi, Mélika Ben Ahmed, Mélika Ben Ahmed, Mélika Ben Ahmed   +25 more
doaj   +1 more source

Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy [PDF]

, 2012
Treatment-resistant muscle wasting is an increasingly recognized problem in idiopathic inflammatory myopathy (IIM). TNF-α is thought to induce muscle catabolism via activation of nuclear factor-kappa B (NF-κB). Several genes share homology with the NF-κB
Ollier, WE, Gunawardena, H, Betteridge, Z, Fertig, N, UK Adult Onset Myositis Immunogenetic Consortium and UK Juvenile, Wedderburn, LR, Platt, H, Li, CK, Varsani, H, Cooper, RG, Oddis, CV, McHugh, NJ, Chinoy, H   +12 more
core  

Scleromyxedema and inflammatory myopathy: A clinicopathology study of three patients

, 1986
Scleromyxedema (lichen myxedematosus is a rare cutaneous manifestation in patients with idiopathic inflammatory myopathy. The clinical and histological findings in three patients with this association are presented. Two patients had a severe inflammatory
Mastaglia, F.L., Cheah, P.S., Zilko, P.J., Ojeda, V.J., Harvey, J.M.   +4 more
core  

Causality between autoimmune diseases and breast cancer: a two-sample Mendelian randomization study in a European population

Discover Oncology
Background The incidence of autoimmune diseases and breast cancer is significantly higher in women compared to men. Previous observational studies have not conclusively determined the relationship between these two conditions.
Hengheng Zhang, Guoshuang Shen, Ping Yang, Meijie Wu, Jinming Li, Zitao Li, Fuxing Zhao, Hongxia Liang, Mengting Da, Ronghua Wang, Chengrong Zhang, Jiuda Zhao, Yi Zhao   +12 more
doaj   +1 more source

Rare Anti-HMGCR-Induced Immune-Mediated Necrotising Myopathy: A Case Report and Literature Review

European Medical Journal
An acute necrotising myopathy is a distinct form of uncommon muscle disease characterised by the rapid advancement of weakness affecting the limbs, neck, pharyngeal, respiratory, and occasionally cardiac muscles.
Thirugnanasambandam Thayumanavan, Anjali Bhardwaj, Abhishek Bhatnagar, Shariq Shamim   +3 more
doaj   +1 more source

Necrotising myopathy, an unusual presentation of a steroid-responsive myopathy

, 2003
Objective To evaluate the clinical features, muscle pathology and response to treatment in patients with a necrotising myopathy, without mononuclear cell infiltrates.
Wokke, JHJ, Hoogendijk, JE, de Visser, M, Wintzen, AR, Bronner, IM, van der Meulen, MFG, Linssen, WHJP   +6 more
core   +1 more source