Results 91 to 100 of about 18,065 (215)

Anti-Signal Recognition Particle Myopathy in a Geriatric Patient

European Journal of Case Reports in Internal Medicine, 2015
Anti-signal recognition particle (SRP) myopathy is a rare idiopathic inflammatory myositis that usually affects middle-age women, and is characterized by rapidly progressive proximal and symmetrical muscle weakness, elevated creatine kinase levels ...
Diana Marques Ferreira, Patrícia Afonso Mendes, António Aragão, Manuel Teixeira Veríssimo, Armando Carvalho   +4 more
doaj   +1 more source

Myocarditis, disseminated infection, and early viral persistence following experimental coxsackievirus B infection of cynomolgus monkeys. [PDF]

, 2013
Coxsackievirus B (CVB) infection is a common cause of acute viral myocarditis. The clinical presentation of myocarditis caused by this enterovirus is highly variable, ranging from mildly symptoms to complete hemodynamic collapse.
Blanchard, James, Bohm, Rudolf, Cammock, Cheryl E, Halnon, Nancy J, Krogstad, Paul A, Lai, Chi, Miller, Christopher J, Skoczylas, Jill   +7 more
core   +2 more sources

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Inflammatory Myopathies with Cutaneous Involvement: from Diagnosis to Therapy

Folia Medica, 2017
The group of idiopathic inflammatory myopathies (IIM) include various disorders of skeletal muscles with or without skin involvement. The most common types are dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and necrotizing ...
Dourmishev Lyubomir A.
doaj   +1 more source

Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation [PDF]

, 2010
Introduction: The endoplasmic reticulum (ER) stress-response, evoked in mice by the overexpression of class I major histocompatibility complex antigen (MHC-I), was proposed as a major mechanism responsible for skeletal muscle damage and dysfunction in ...
Maurizio Vitadello, Andrea Doria, Elena Tarricone, Anna Ghirardello, Luisa Gorza   +4 more
core   +2 more sources

Collagen and microvascular alterations contribute to neuromuscular degeneration and disease progression in chronic intestinal pseudo‐obstruction

Journal of Internal Medicine, Volume 299, Issue 5, Page 587-603, May 2026.
Abstract Background Chronic intestinal pseudo‐obstruction (CIPO) is a severe gastrointestinal motility disorder that may be idiopathic or associated with systemic disease. In idiopathic cases, the pathophysiological mechanisms remain poorly defined. Although mutations in angiogenic factors have been reported in mitochondrial forms of CIPO, their role ...
Elisa Boschetti, Irene Neri, Leonardo Caporali, Elena Bonora, Carolina Malagelada, Claudio Fiorini, Danara Ormanbekova, Alessandro Berghella, Roberto D'Angelo, Rita Rinaldi, Cristiana Caliceti, Anna Costanzini, Mirella Falconi, Vincenzo Stanghellini, Stefano Ratti, Lucia Manzoli, Valerio Carelli, Roberto De Giorgio   +17 more
wiley   +1 more source

History of diagnosis on idiopathic inflammatory myopathy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
The idiopathic inflammatory myopathy (IIM) is a group of clinically heterogeneous, autoimmune-mediated disorders characterized by inflammation of muscle, elevated creatine kinase (CK), interstitial lung disease and other organ systems involvement ...
Wei ZHANG
doaj  

Progress of imaging findings in idiopathic inflammatory myopathy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Idiopathic inflammatory myopathy (IIM) is a group of autoimmune diseases with clinical features presented with muscle weakness and inflammation in muscle.
Wei⁃yi YU, Ye⁃li ZHU, Chao YUAN, Hui ZHENG, Yuan⁃kui WU, Dao⁃kun REN, Jian⁃ping WANG, Lu⁃fei ZHANG, Ye HE, Su⁃yue PAN, Hai⁃shan JIANG   +10 more
doaj  

Necrotizing autoimmune myopathy: Clinicopathologic study from a single tertiary care centre

Annals of Indian Academy of Neurology, 2018
Background: Idiopathic inflammatory myopathies (IIMs) are a group of chronic, autoimmune disorders which include a new entity, necrotizing autoimmune myopathy (NAM). NAM lacks inflammation and presents with markedly elevated creatinine phosphokinase (CPK)
Sobiya Mahnaz Ayesha, A K Meena, Navatha Vangala, Liza Rajasekhar, Subhash Kaul, Rupam Borgahain, Megha S Uppin   +6 more
doaj   +1 more source