Results 81 to 90 of about 11,875 (182)

Treatment of idiopathic inflammatory myopathies

Joint Bone Spine
Adult idiopathic inflammatory myopathies (IIMs) are rare autoimmune disorders affecting multiple organs, making diagnosis and treatment challenging. Current management relies on immunosuppressants like corticosteroids, methotrexate, azathioprine, mycophenolate mofetil, rituximab, and intravenous immunoglobulin, though treatment responses vary across ...
Raquel Campanilho-Marques, João Eurico Fonseca, Pedro M. Machado   +2 more
openaire   +2 more sources

Anti-HMGCR myopathy: a first case report from North Africa and literature insights

Frontiers in Immunology
Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy is a rare idiopathic inflammatory myopathy characterized by severe muscle damage and minimal extra-muscular involvement.
Houssem Abida, Houssem Abida, Imen Zamali, Imen Zamali, Imen Zamali, Imène Rachdi, Imène Rachdi, Zakaria Saied, Zakaria Saied, Ahlem Ben Hmid, Ahlem Ben Hmid, Ahlem Ben Hmid, Samar Samoud, Samar Samoud, Yousr Galai, Fatma Daoud, Fatma Daoud, Fatma Boussema, Fatma Boussema, Samia Ben Sassi, Samia Ben Sassi, Zohra Aydi, Zohra Aydi, Mélika Ben Ahmed, Mélika Ben Ahmed, Mélika Ben Ahmed   +25 more
doaj   +1 more source

Rare Anti-HMGCR-Induced Immune-Mediated Necrotising Myopathy: A Case Report and Literature Review

European Medical Journal
An acute necrotising myopathy is a distinct form of uncommon muscle disease characterised by the rapid advancement of weakness affecting the limbs, neck, pharyngeal, respiratory, and occasionally cardiac muscles.
Thirugnanasambandam Thayumanavan, Anjali Bhardwaj, Abhishek Bhatnagar, Shariq Shamim   +3 more
doaj   +1 more source

Causality between autoimmune diseases and breast cancer: a two-sample Mendelian randomization study in a European population

Discover Oncology
Background The incidence of autoimmune diseases and breast cancer is significantly higher in women compared to men. Previous observational studies have not conclusively determined the relationship between these two conditions.
Hengheng Zhang, Guoshuang Shen, Ping Yang, Meijie Wu, Jinming Li, Zitao Li, Fuxing Zhao, Hongxia Liang, Mengting Da, Ronghua Wang, Chengrong Zhang, Jiuda Zhao, Yi Zhao   +12 more
doaj   +1 more source

Pericarditis as the Initial Manifestation of Antisynthetase Syndrome: A Case Report

Case Reports in Rheumatology
Antisynthetase syndrome is a subtype of idiopathic inflammatory myopathy characterized by clinical manifestations that include myositis with a distinctive muscle biopsy pattern. Cardiac involvement has traditionally been considered a rare feature of this
Gianni Lucchetti, Per Sundbom
doaj   +1 more source

Beyond the Generalized Weakness: A Rare Case of Statin-Induced Immune-Mediated Necrotizing Myopathy

Journal of Investigative Medicine High Impact Case Reports
Statin-induced immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy associated with statin exposure and characterized by positive anti-hydroxymethylglutaryl coenzyme A reductase antibodies. Here, we describe a
Leo Sakai DO, Hana Kazbour MD, James Huang MD   +2 more
doaj   +1 more source

An update on the pathogenesis of idiopathic inflammatory myopathies

Current Opinion in Rheumatology
Purpose of review As the question of the pathogenesis of inflammatory myopathies remains unanswered, there has been a significant effort in recent years to investigate various components of the innate and adaptive immune systems, with evidence pointing that they work together to initiate and propagate the autoimmune response ...
openaire   +3 more sources

Serum Endothelin-1 Is Associated With Interstitial Lung Disease in Idiopathic Inflammatory Myopathy. [PDF]

ACR Open Rheumatol
Lv Y, Li W, Jiang Y, Huang Z, Men L, Zhang S.   +5 more
europepmc   +1 more source

Machine learning for predicting acute exacerbation and mortality in idiopathic inflammatory myopathy-associated interstitial lung disease. [PDF]

Front Med (Lausanne)
Lu S, Zheng M, Miao S, Zhu X, Zhu G, Ye L, Chen D.   +6 more
europepmc   +1 more source

Multimodal ultrasound for precise quantitative evaluation of diaphragmatic lesions in idiopathic inflammatory myopathy: a promising assessment tool. [PDF]

Quant Imaging Med Surg
Tian M, Shu M, Guo R, Cao S, Qiu L, Tang Y.   +5 more
europepmc   +1 more source