Siltuximab monotherapy improves progression free survival compared to rituximab-based therapies in patients with idiopathic multicentric Castleman disease; indirect comparison of studies using single-arm metanalysis method and the generalized linear mixed model. [PDF]
Siltuximab is the only approved treatment for idiopathic multicentric Castleman Disease but in many countries the only available treatment is rituximab based.
Karatisidis L +9 more
europepmc +2 more sources
Siltuximab in Idiopathic Multicentric Castleman Disease: Real-World Experience. [PDF]
Castleman disease (CD) is a very rare, non-malignant lymphoproliferative disorder that can be classified as unicentric or multicentric (MCD). MCD is associated with systemic symptoms, including organ dysfunction due to cytokine dysregulation, primarily interleukin-6 (IL-6).
Jitaru C +26 more
europepmc +3 more sources
Computed tomography findings of idiopathic multicentric Castleman disease subtypes. [PDF]
This study retrospectively evaluated the computed tomography (CT) findings of idiopathic multicentric Castleman disease (iMCD) at a single center and compared the CT findings of iMCD-TAFRO with those of iMCD-non-TAFRO. CT images obtained within 30 days before diagnostic confirmation were reviewed for 20 patients with iMCD (8 men and 12 women, mean age ...
Iguchi T +9 more
europepmc +3 more sources
Diagnostic challenges of the idiopathic plasmacytic lymphadenopathy (IPL) subtype of idiopathic multicentric Castleman disease (iMCD): Factors to differentiate from IgG4-related disease. [PDF]
Nishikori A +15 more
europepmc +3 more sources
An Unusual Case of HHV-8 Negative, Idiopathic, Multicentric Castleman Disease Following Chronic Lymphocytic Leukaemia. [PDF]
Background: Castleman disease is a rare condition characterised by polytypic lymphocytes proliferation and lymphadenopathy generally with a benign course.
Sansen PY +6 more
europepmc +2 more sources
Novel insights and therapeutic approaches in idiopathic multicentric Castleman disease [PDF]
David C Fajgenbaum
exaly +2 more sources
Idiopathic Multicentric Castleman Disease Mimicking Orbital Pseudotumor [PDF]
Sang Hoon Han +2 more
openalex +2 more sources
Idiopathic multicentric Castleman disease and its rare association with peripheral neuropathy and stroke [PDF]
Hatta B +5 more
europepmc +2 more sources
The Evolution and Recent Advances in Diagnostic Criteria for Idiopathic Multicentric Castleman Disease. [PDF]
Idiopathic Multicentric Castleman Disease. ABSTRACT Idiopathic multicentric Castleman disease (iMCD) is a rare cytokine‐driven disorder characterized by systemic inflammation, organ dysfunction, and altered lymph node microscopic architecture. Over the past decade, diagnostic criteria have evolved significantly, integrating clinical, histopathological,
Alnoor F +11 more
europepmc +2 more sources
Plasma Cell-rich Nephritis with a Systemic Polyclonal Lymphoproliferative Disorder, Mimicking Idiopathic Multicentric Castleman Disease, Systemic Lupus Erythematosus, and IgG4-related Disease. [PDF]
Hebisawa Y +4 more
europepmc +3 more sources

