Results 161 to 170 of about 13,037 (197)

A Randomized Trial of Shunting for Idiopathic Normal Pressure Hydrocephalus

New England Journal of Medicine
Background: Idiopathic normal pressure hydrocephalus (iNPH) is a neurologic disorder of impaired gait, balance, cognition, and bladder control in older adults that is treated with shunt surgery.
Mark G Luciano, Michael A. Williams, Mark G Hamilton, Heather L Katzen, N. Dasher, A. Moghekar, Jun Hua, J. Malm, Anders Eklund, Naomi Alpert Abel, A. Raslan, Benjamin D. Elder, Jesse J Savage, Daniel L Barrow, K. Shahlaie, H. Jensen, Thomas J Zwimpfer, Jessica Wollett, Dan Hanley, R. Holubkov   +19 more
semanticscholar   +1 more source

The Efficacy of Endoscopic Third Ventriculostomy for Idiopathic Normal Pressure Hydrocephalus.

World Neurosurgery, 2023
Recently, intervention with endoscopic third ventriculostomy (ETV) for patients with idiopathic normal pressure hydrocephalus (iNPH) has emerged as a potential minimally invasive alternative to traditional treatments (ventriculoperitoneal shunting).
Neel H. Mehta, A. Greenberg, K. Kahle
semanticscholar   +1 more source

Guidelines for Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus.

Neurosurgery clinics of North America
In 1965, Hakim and Adams described 3 patients with normal pressure hydrocephalus who responded to treatment with a ventriculoatrial shunt. Afterward the adoption of shunt treatment without clear diagnostic criteria and surgical techniques resulted in ...
Mark G. Hamilton, Michael A. Williams, Sara Edwards, M. Tullberg   +3 more
semanticscholar   +1 more source

Associations of ventriculomegaly and white matter hyperintensities with glymphatic dysfunction in idiopathic normal pressure hydrocephalus

European Radiology
To investigate glymphatic function in idiopathic normal pressure hydrocephalus (iNPH) using the diffusion tensor image analysis along the perivascular space (DTI-ALPS) method and to explore the associations of ALPS index with ventriculomegaly and white ...
Qian Wu, Jiakuan Chen, Xiaolin Yang, Xiejun Zhang, Wenjie He, Jun Xia   +5 more
semanticscholar   +1 more source

Health-Related Quality of Life and Role of Surgical Treatment in Idiopathic Normal Pressure Hydrocephalus: A Systematic Review.

World Neurosurgery, 2023
OBJECTIVE While shunting has been shown to ameliorate symptoms in idiopathic normal pressure hydrocephalus (iNPH), its impact on health-related quality of life (HRQoL) has yet to be fully elucidated. Patient and caregiver subjective life satisfaction, as
Fabio Torregrossa, Felice Buscemi, V. Gulino, B. Campisi, Gaia Teresi, G. Grasso   +5 more
semanticscholar   +1 more source

The effectiveness of various CSF diversion surgeries in idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

EClinicalMedicine
Summary Background Idiopathic normal pressure hydrocephalus (iNPH) is commonly treated using cerebrospinal fluid (CSF) diversion procedures, most commonly ventriculoperitoneal (VP) but also lumboperitoneal (LP), ventriculoatrial (VA) shunting, and ...
A. Salih, Aksaan Arif, Madhur Varadpande, R. T. Fernandes, Dragan Janković, D. Kalasauskas, M. Ottenhausen, Andreas Kramer, F. Ringel, S. Thavarajasingam   +9 more
semanticscholar   +1 more source

Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis.

Cerebral Cortex, 2023
Idiopathic normal pressure hydrocephalus is a disorder of unknown pathophysiology whose diagnosis is paradoxically made by a positive response to its proposed treatment with cerebrospinal fluid diversion. There are currently no idiopathic normal pressure
A. Greenberg, Neel H. Mehta, K. Mekbib, E. Kiziltug, Hannah R Smith, Bradley T. Hyman, Diane Chan, William T. Curry, Steven E. Arnold, Matthew P Frosch, P. Duy, Kristopher T. Kahle   +11 more
semanticscholar   +1 more source

Automated Idiopathic Normal Pressure Hydrocephalus Diagnosis via Artificial Intelligence–Based 3D T1 MRI Volumetric Analysis

American Journal of Neuroradiology
BACKGROUND AND PURPOSE: Idiopathic normal pressure hydrocephalus (iNPH) is reversible dementia that is underdiagnosed. The purpose of this study was to develop an automated diagnostic method for iNPH using artificial intelligence techniques with a T1 ...
Joonhyung Lee, Dana Kim, C. H. Suh, S. Yun, Kyu Sung Choi, Seungjun Lee, Wooseok Jung, Jinyoung Kim, H. Heo, W. H. Shim, S. Jo, S. J. Chung, Jae-Sung Lim, Ho Sung Kim, Sang Joon Kim, Jae-Hong Lee   +15 more
semanticscholar   +1 more source

Idiopathic Normal Pressure Hydrocephalus

Neurosurgery Quarterly, 2011
The syndrome of idiopathic normal pressure hydro- cephalus was first described in 1965, but 45 years later controversies still exist with regard to its cause, progression, differential diagnosis, and best treatment strategies. Its incidence may be underestimated and its importance increasing because of the aging population.
Andrew Tarnaris, Michael A. Williams
openaire   +1 more source

Cortical atrophy distinguishes idiopathic normal-pressure hydrocephalus from progressive supranuclear palsy: A machine learning approach.

Parkinsonism & Related Disorders, 2022
INTRODUCTION Progressive supranuclear palsy (PSP) and idiopathic normal pressure hydrocephalus (iNPH) share several clinical and radiological features, making the differential diagnosis challenging.
M. Bianco, A. Quattrone, Alessia Sarica, B. Vescio, J. Buonocore, M. G. Vaccaro, Federica Aracri, Camilla Calomino, V. Gramigna, A. Quattrone   +9 more
semanticscholar   +1 more source