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Idiopathic normal pressure hydrocephalus and systemic hypertension
Neurology, 1987Nineteen patients with idiopathic normal pressure hydrocephalus (NPH) were treated with intraventricular shunts. Ten of the 14 who improved and 14 of the total group had systemic hypertension. The prevalence of hypertension in both the improved and whole NPH groups was significantly greater than in a control group with dementia (N = 122) and the ...
N R, Graff-Radford, J C, Godersky
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Idiopathic Normal Pressure Hydrocephalus
2012Idiopathic normal pressure hydrocephalus (INPH) is characterized by the clinical triad of gait disturbance, cognitive dysfunction, and urinary symptoms, observed in the context of enlargement of the cerebral ventricular system. Mean age of onset is approximately 60 years, which complicates the diagnosis since there is the potential for multiple age ...
Lisa D. Ravdin, Heather L. Katzen
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Familial Occurrence of Idiopathic Normal-Pressure Hydrocephalus
Archives of Neurology, 1984Shunt-responsive normal-pressure hydrocephalus developed in a 67-year-old man and in his 74-year-old sister. To our knowledge, a familial association in this disorder has not been reported previously.
R K, Portenoy, A, Berger, E, Gross
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Natural course of idiopathic normal pressure hydrocephalus
Journal of Neurology, Neurosurgery & Psychiatry, 2013The natural course of idiopathic normal pressure hydrocephalus (iNPH) has not been thoroughly studied. The consequences of postponing shunt treatment are largely unknown. We aimed to describe the effects of waiting for more than 6 months before surgery and to compare the outcome with that seen in patients who waited for less than 3 months.33 patients ...
Kerstin, Andrén +3 more
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[Idiopathic normal pressure hydrocephalus].
Praxis, 2009Normal pressure hydrocephalus (NPH) is characterized by the classic triad of symptoms including gait disturbance, urinary incontinence, and dementia. Gait impairment represents the cardinal symptom. NPH is associated with a radiological verifiable ventriculomegaly in the absence of elevated cerebrospinal fluid (CSF) pressure.
O P, Gautschi +4 more
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A Glycan Marker for Idiopathic Normal Pressure Hydrocephalus
2014Two glycan isoforms of transferrin (Tf), Tf-1 and Tf-2, were found in cerebrospinal fluid (CSF). Tf-1 concentration in CSF was reduced in idiopathic normal pressure hydrocephalus (iNPH), an elderly dementia caused by abnormal metabolism of CSF, whereas Tf-2 concentration was not. The reduction of Tf-1 concentration was not found in Alzheimer’s disease,
Kyoka Hoshi +13 more
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The “Reversible” Dementia of Idiopathic Normal Pressure Hydrocephalus
The Consultant Pharmacist, 2006Unstable gait, urinary incontinence, confusion. Most health care practitioners, including consultant pharmacists, immediately associate these problems with the signs and symptoms of vascular or Alzheimer's dementia. But, there also exists a small population of patients for whom these signs and symptoms are related to another-often curable-problem ...
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Idiopathic normal-pressure hydrocephalus
Journal of Neurosurgery, 1980✓ Of 62 patients given shunts for normal-pressure hydrocephalus of idiopathic type, 46.8% showed some improvement and 27.4% enjoyed virtually complete recovery. The best clinical predictor of good response was the complete triad of memory difficulty, gait disorder, and urine incontinence; 61.2% of patients with this combination of symptoms improved ...
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Idiopathic Normal Pressure Hydrocephalus
Contemporary Neurosurgery, 2014Teruo Kimura +2 more
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Idiopathic Normal-Pressure Hydrocephalus
New England Journal of MedicineMark D, Johnson, Michael A, Williams
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