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Multiscale Single-Cell Assessment of the Fibrotic Niche in Idiopathic Pulmonary Fibrosis

open access: yes
Liu B   +17 more
europepmc   +1 more source

Idiopathic Pulmonary Fibrosis [PDF]

open access: possibleNew England Journal of Medicine, 2018
Idiopathic Pulmonary Fibrosis Idiopathic pulmonary fibrosis appears to be increasing in incidence. It requires early recognition and intervention with supportive care and pharmacologic agents to forestall its progression. Lung transplantation may be curative, but the disease may recur in transplanted lungs.
Poletti Venerino   +2 more
openaire   +8 more sources
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Idiopathic Pulmonary Fibrosis

Seminars in Respiratory and Critical Care Medicine, 2012
Idiopathic pulmonary fibrosis (IPF) is a specific form of progressive, chronic fibrosing interstitial lung disease occurring primarily in older adults and limited to the lungs. The prognosis is dire, with half of all patients progressing to death from respiratory failure within 3 to 5 years from initial diagnosis. The pathogenesis of IPF is complex and
Jessica M. Adkins, Harold R. Collard
openaire   +5 more sources

Idiopathic Pulmonary Fibrosis

Annual Review of Medicine, 1993
Idiopathic pulmonary fibrosis kills half of its victims within five years of diagnosis. Currently available treatment regimens are disappointing, and the incidence of the disease appears to be increasing. Newer techniques of imaging coupled with laboratory advances in molecular and cellular biology may produce new strategies for modulating the disease ...
Owen J, Dempsey, David, Miller
openaire   +3 more sources

Idiopathic Pulmonary Fibrosis

Journal of Thoracic Imaging, 2016
Idiopathic pulmonary fibrosis (IPF) is the most common fibrosing lung disease and is associated with a very poor prognosis. IPF manifests histopathologically as usual interstitial pneumonia (UIP) and as subpleural and basal predominant reticulation with honeycombing on high-resolution computed tomography (HRCT) of the chest.
Maria D. Martin   +2 more
openaire   +3 more sources

Idiopathic Pulmonary Fibrosis

New England Journal of Medicine, 2001
Idiopathic pulmonary fibrosis is a rapidly progressive illness of unknown cause characterized by sequential acute lung injury with subsequent scarring and end-stage lung disease. Treatment at present remains largely supportive, with evidence that patients' satisfaction and survival may be improved by referral to centers specializing in the evaluation ...
Thomas J. Gross, Gary W. Hunninghake
openaire   +3 more sources

Treatments for Idiopathic Pulmonary Fibrosis

New England Journal of Medicine, 2014
To the Editor: In reporting the results of the INPULSIS-1 and INPULSIS-2 trials, Richeldi et al. (May 29 issue) 1 describe the use of nintedanib in the treatment of idiopathic pulmonary fibrosis. In the same issue, King et al. 2 report the results of the Assessment of Pirfenidone to Confirm Efficacy and Safety in Idiopathic Pulmonary Fibrosis (ASCEND ...
Shinyu Izumi   +2 more
openaire   +8 more sources

Idiopathic pulmonary fibrosis

Expert Review of Respiratory Medicine, 2007
Idiopathic pulmonary fibrosis (IPF; also known as cryptogenic fibrosing alveolitis) is a distinctive type of chronic fibrosing interstitial pneumonia of unknown cause associated with the histological pattern usual interstitial pneumonia (UIP). UIP is a distinct histological pattern observed in IPF but may also be found in other etiologies.
Joseph P, Lynch   +4 more
openaire   +2 more sources

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