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Seminars in Respiratory and Critical Care Medicine, 2012
Idiopathic pulmonary fibrosis (IPF) is a specific form of progressive, chronic fibrosing interstitial lung disease occurring primarily in older adults and limited to the lungs. The prognosis is dire, with half of all patients progressing to death from respiratory failure within 3 to 5 years from initial diagnosis. The pathogenesis of IPF is complex and
Jessica M. Adkins, Harold R. Collard
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Idiopathic pulmonary fibrosis (IPF) is a specific form of progressive, chronic fibrosing interstitial lung disease occurring primarily in older adults and limited to the lungs. The prognosis is dire, with half of all patients progressing to death from respiratory failure within 3 to 5 years from initial diagnosis. The pathogenesis of IPF is complex and
Jessica M. Adkins, Harold R. Collard
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Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis.
Annual Review of Pathology, 2021The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in the context of predisposing factors (e.g., genetic, environmental ...
B. Moss, S. Ryter, I. Rosas
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Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline
American Journal of Respiratory and Critical Care Medicine, 2018Background: This document provides clinical recommendations for the diagnosis of idiopathic pulmonary fibrosis (IPF). It represents a collaborative effort between the American Thoracic Society, European Respiratory Society, Japanese Respiratory Society ...
G. Raghu +33 more
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Annual Review of Medicine, 1993
Idiopathic pulmonary fibrosis kills half of its victims within five years of diagnosis. Currently available treatment regimens are disappointing, and the incidence of the disease appears to be increasing. Newer techniques of imaging coupled with laboratory advances in molecular and cellular biology may produce new strategies for modulating the disease ...
Owen J, Dempsey, David, Miller
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Idiopathic pulmonary fibrosis kills half of its victims within five years of diagnosis. Currently available treatment regimens are disappointing, and the incidence of the disease appears to be increasing. Newer techniques of imaging coupled with laboratory advances in molecular and cellular biology may produce new strategies for modulating the disease ...
Owen J, Dempsey, David, Miller
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Journal of Thoracic Imaging, 2016
Idiopathic pulmonary fibrosis (IPF) is the most common fibrosing lung disease and is associated with a very poor prognosis. IPF manifests histopathologically as usual interstitial pneumonia (UIP) and as subpleural and basal predominant reticulation with honeycombing on high-resolution computed tomography (HRCT) of the chest.
Maria D. Martin +2 more
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Idiopathic pulmonary fibrosis (IPF) is the most common fibrosing lung disease and is associated with a very poor prognosis. IPF manifests histopathologically as usual interstitial pneumonia (UIP) and as subpleural and basal predominant reticulation with honeycombing on high-resolution computed tomography (HRCT) of the chest.
Maria D. Martin +2 more
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New England Journal of Medicine, 2001
Idiopathic pulmonary fibrosis is a rapidly progressive illness of unknown cause characterized by sequential acute lung injury with subsequent scarring and end-stage lung disease. Treatment at present remains largely supportive, with evidence that patients' satisfaction and survival may be improved by referral to centers specializing in the evaluation ...
Thomas J. Gross, Gary W. Hunninghake
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Idiopathic pulmonary fibrosis is a rapidly progressive illness of unknown cause characterized by sequential acute lung injury with subsequent scarring and end-stage lung disease. Treatment at present remains largely supportive, with evidence that patients' satisfaction and survival may be improved by referral to centers specializing in the evaluation ...
Thomas J. Gross, Gary W. Hunninghake
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Treatments for Idiopathic Pulmonary Fibrosis
New England Journal of Medicine, 2014To the Editor: In reporting the results of the INPULSIS-1 and INPULSIS-2 trials, Richeldi et al. (May 29 issue) 1 describe the use of nintedanib in the treatment of idiopathic pulmonary fibrosis. In the same issue, King et al. 2 report the results of the Assessment of Pirfenidone to Confirm Efficacy and Safety in Idiopathic Pulmonary Fibrosis (ASCEND ...
Shinyu Izumi +2 more
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Expert Review of Respiratory Medicine, 2007
Idiopathic pulmonary fibrosis (IPF; also known as cryptogenic fibrosing alveolitis) is a distinctive type of chronic fibrosing interstitial pneumonia of unknown cause associated with the histological pattern usual interstitial pneumonia (UIP). UIP is a distinct histological pattern observed in IPF but may also be found in other etiologies.
Joseph P, Lynch +4 more
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Idiopathic pulmonary fibrosis (IPF; also known as cryptogenic fibrosing alveolitis) is a distinctive type of chronic fibrosing interstitial pneumonia of unknown cause associated with the histological pattern usual interstitial pneumonia (UIP). UIP is a distinct histological pattern observed in IPF but may also be found in other etiologies.
Joseph P, Lynch +4 more
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Idiopathic Pulmonary Fibrosis and Progressive Pulmonary Fibrosis
Immunology and Allergy Clinics of North America, 2023Idiopathic pulmonary fibrosis (IPF), a common interstitial lung disease (ILD), is a chronic, progressive fibrosing interstitial pneumonia, with an unknown cause. IPF has been linked to several genetic and environmental risk factors. Disease progression is common and associated with worse outcomes.
Rachel, Strykowski, Ayodeji, Adegunsoye
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Clinics in Chest Medicine, 1982
SUMMARY Idiopathic pulmonary fibrosis is a precise syndrome defined by clinical, roentgenographic, physiologic, and histopathologic features. Clinically, most patients have a nonproductive cough and dyspnea on exertion. The most common physical finding is the presence of crackles over the lower portions of both lungs; also, there may be clubbing ...
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SUMMARY Idiopathic pulmonary fibrosis is a precise syndrome defined by clinical, roentgenographic, physiologic, and histopathologic features. Clinically, most patients have a nonproductive cough and dyspnea on exertion. The most common physical finding is the presence of crackles over the lower portions of both lungs; also, there may be clubbing ...
openaire +3 more sources