Results 41 to 50 of about 207,794 (393)

The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference [PDF]

, 2010
The response characteristics of the 6 minute walk test (6MWT) in studies of idiopathic pulmonary fibrosis (IPF) are only poorly understood, and the change in walk distance that constitutes the minimum important difference (MID) over time is ...
Behr, Jürgen, Brown, Kevin K., du Bois, Roland M., King, Talmadge E., Raghu, Ganesh, Swigris, Jeffrey J., Wamboldt, Frederick S.   +6 more
core   +1 more source

Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]

, 2010
Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica, Dumitrascu, Rio, Eickelberg, Oliver, Grimminger, Friedrich, Königshoff, Melanie, Reiter, Rudolf, Schermuly, Ralph Theo, Seeger, Werner, Udalov, Sergey   +8 more
core   +1 more source

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

Science Advances, 2020
Human lung single-cell atlas reveals the complexity and diversity of aberrant cellular populations in pulmonary fibrosis. We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, by profiling 312,928 cells
T. Adams, J. Schupp, S. Poli, Ehab A. Ayaub, N. Neumark, F. Ahangari, S. Chu, B. Raby, G. DeIuliis, Michael Januszyk, Qiaonan Duan, H. Arnett, Asim Siddiqui, G. Washko, R. Homer, Xiting Yan, I. Rosas, N. Kaminski   +17 more
semanticscholar   +1 more source

Quantitative computed tomography predicts outcomes in idiopathic pulmonary fibrosis

Respirology (Carlton South. Print), 2022
Prediction of disease course in patients with progressive pulmonary fibrosis remains challenging. The purpose of this study was to assess the prognostic value of lung fibrosis extent quantified at computed tomography (CT) using data‐driven texture ...
S. Humphries, J. Mackintosh, H. Jo, S. Walsh, Mario Silva, L. Calandriello, Sally Chapman, Samantha J Ellis, I. Glaspole, N. Goh, C. Grainge, P. Hopkins, G. Keir, Y. Moodley, P. Reynolds, E. Walters, D. Baraghoshi, A. Wells, D. Lynch, T. Corte   +19 more
semanticscholar   +1 more source

IDIOPATHIC PULMONARY FIBROSIS. CORRECTION OF ERRORS

Вестник рентгенологии и радиологии, 2018
Substantial changes have been recently made in the concept of the diagnosis of idiopathic pulmonary fibrosis. The concept of disease pathogenesis and the pathomorphologic criteria for diagnosing usual interstitial pneumonia have been revised.
A. L. Yudin, Yu. A. Abovich, N. I. Afanas’eva   +2 more
doaj   +1 more source

A review of current studies on cellular and molecular mechanisms underlying pulmonary fibrosis induced by chemicals [PDF]

Environmental Health and Toxicology, 2018
Several studies showed that the inflammatory and fibrotic responses induced by polyhexamethylene guanidine phosphate (PHMG-p) were similar to those observed for idiopathic pulmonary fibrosis in South Korea in 2011.
Ha Ryong Kim, Da Young Shin, Kyu Hyuck Chung   +2 more
doaj   +1 more source

Immune dysregulation as a driver of idiopathic pulmonary fibrosis.

Journal of Clinical Investigation, 2021
Idiopathic pulmonary fibrosis (IPF) affects hundreds of thousands of people worldwide, reducing their quality of life and leading to death from respiratory failure within years of diagnosis.
K. Shenderov, S. Collins, J. Powell, M. Horton   +3 more
semanticscholar   +1 more source

Rethinking Idiopathic Pulmonary Fibrosis

Clinics in Chest Medicine, 2021
Idiopathic pulmonary fibrosis (IPF) is a devastating disease for patients and their loved ones. Since initial efforts to characterize this disease in the 1960s, understanding of IPF has evolved considerably. Such evolution has continually challenged prior diagnostic and treatment paradigms, ushering in an era of higher confidence diagnoses with less ...
Oldham, Justin M, Vancheri, Carlo
openaire   +2 more sources

Akt1 regulates pulmonary fibrosis via modulating IL-13 expression in macrophages

Innate Immunity, 2019
Idiopathic pulmonary fibrosis is a progressive interstitial pneumonia characterised by fibroblast accumulation, collagen deposition and extracellular matrix (ECM) remodelling.
Yunjuan Nie, Yudong Hu, Kaikai Yu, Dan Zhang, Yinze Shi, Yaolin Li, Lei Sun, Feng Qian   +7 more
doaj   +1 more source

Inflammatory bowel disease and risk of idiopathic pulmonary fibrosis: A protocol for systematic review and meta-analysis.

PLoS ONE, 2022
IntroductionInflammatory bowel disease is a relapsing chronic gastrointestinal inflammatory disease. Idiopathic pulmonary fibrosis is a rare but serious extraintestinal pulmonary manifestation of inflammatory bowel disease.
Jiali Wang, Fushun Kou, Xiao Han, Lei Shi, Rui Shi, Zhibin Wang, Tangyou Mao, Junxiang Li   +7 more
doaj   +1 more source