Results 41 to 50 of about 106,218 (349)

Recent advances in understanding idiopathic pulmonary fibrosis [PDF]

, 2016
Despite major research efforts leading to the recent approval of pirfenidone and nintedanib, the dismal prognosis of idiopathic pulmonary fibrosis (IPF) remains unchanged.
Daccord, C, Maher, TM
core   +3 more sources

Inflammatory bowel disease and risk of idiopathic pulmonary fibrosis: A protocol for systematic review and meta-analysis.

PLoS ONE, 2022
IntroductionInflammatory bowel disease is a relapsing chronic gastrointestinal inflammatory disease. Idiopathic pulmonary fibrosis is a rare but serious extraintestinal pulmonary manifestation of inflammatory bowel disease.
Jiali Wang, Fushun Kou, Xiao Han, Lei Shi, Rui Shi, Zhibin Wang, Tangyou Mao, Junxiang Li   +7 more
doaj   +1 more source

Pulmonary fibrosis: “idiopathic” is not “cryptogenic” [PDF]

European Respiratory Journal, 2019
The additional argument advanced by Professor Cottin for retention of the term “idiopathic pulmonary fibrosis” is highly persuasivehttp://ow.ly ...
Wells, Athol U, Brown, Kevin K, Flaherty, Kevin R, Kolb, Martin, Thannickal, Victor J, Vancheri C   +5 more
openaire   +3 more sources

Airway measurement by refinement of synthetic images improves mortality prediction in idiopathic pulmonary fibrosis [PDF]

arXiv, 2022
Several chronic lung diseases, like idiopathic pulmonary fibrosis (IPF) are characterised by abnormal dilatation of the airways. Quantification of airway features on computed tomography (CT) can help characterise disease progression. Physics based airway measurement algorithms have been developed, but have met with limited success in part due to the ...
arxiv  

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis [PDF]

, 2017
Background: Neurotrophins (NT) belongs to a family of growth factors which promotes neurons survival and differentiation. Increasing evidence show that NT and their receptor are expressed in lung tissues suggesting a possible role in lung health and ...
Bruno, Pierdonato, Cardillo, Giuseppe, Cherubini, Emanuela, D'Ascanio, Michela, Mancini, Rita, Mariotta, Salvatore, Osman, GIORGIA AMIRA, Ricci, Alberto, Scozzi, Davide   +8 more
core   +1 more source

High complement protein C1q levels in pulmonary fibrosis and non-small cell lung cancer associated with poor prognosis

BMC Cancer, 2022
Background Idiopathic pulmonary fibrosis (IPF) is the most common type of interstitial pneumonia. Lung cancer, mainly non-small cell lung cancer (NSCLC), is a complication of idiopathic pulmonary fibrosis.
Wenxin Kou, Bo Li, Yeifei Shi, Yifan Zhao, Qing Yu, Jianhui Zhuang, Yawei Xu, Wenhui Peng   +7 more
doaj   +1 more source

The 6 minute walk in idiopathic pulmonary fibrosis: longitudinal changes and minimum important difference [PDF]

, 2010
The response characteristics of the 6 minute walk test (6MWT) in studies of idiopathic pulmonary fibrosis (IPF) are only poorly understood, and the change in walk distance that constitutes the minimum important difference (MID) over time is ...
Behr, Jürgen, Brown, Kevin K., du Bois, Roland M., King, Talmadge E., Raghu, Ganesh, Swigris, Jeffrey J., Wamboldt, Frederick S.   +6 more
core   +1 more source

Transcriptional Dynamics of NRF2 Overexpression and KEAP1-NRF2 Inhibitors in Human Cell Line and Primary Lung Cells

Antioxidants
Oxidative stress in the human lung is caused by both internal (e.g., inflammation) and external stressors (smoking, pollution, and infection) to drive pathology in a number of lung diseases.
Corinne Hamblet, Karin Björhall, Susann Busch, Ulf Gehrmann, Lisa Öberg, Rebekka Kubisch-Dohmen, Sonja Haas, Manish K. Aneja, Johannes Geiger, Carsten Rudolph, Ellinor Hornberg   +10 more
doaj   +1 more source

Diabetes Mellitus Contributes to Idiopathic Pulmonary Fibrosis: A Review From Clinical Appearance to Possible Pathogenesis

Frontiers in Public Health, 2020
Diabetes mellitus is a systematic metabolic disease characterized by persistent hyperglycemia, which complications often involve multiple organs and systems including vessels, kidneys, retinas, and nervous system.
Dongguang Wang, Yao Ma, Xiang Tong, Yonggang Zhang, Hong Fan   +4 more
doaj   +1 more source