Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis
British medical journal, 2022 Similarly to idiopathic pulmonary fibrosis (IPF), other interstitial lung diseases can develop progressive pulmonary fibrosis (PPF) characterized by declining lung function, a poor response to immunomodulatory therapies, and early mortality.
Gabrielle Y. Liu +2 more
semanticscholar +1 more source
Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations [PDF]
, 2014 BACKGROUND: Previous studies investigating a genetic basis for idiopathic pulmonary fibrosis (IPF) have focused on resequencing single genes in IPF kindreds or cohorts to determine the genetic contributions to IPF.
Coghlan, Meghan A +8 more
core +3 more sources
IDIOPATHIC PULMONARY FIBROSIS. CORRECTION OF ERRORS
Вестник рентгенологии и радиологии, 2018 Substantial changes have been recently made in the concept of the diagnosis of idiopathic pulmonary fibrosis. The concept of disease pathogenesis and the pathomorphologic criteria for diagnosing usual interstitial pneumonia have been revised.
A. L. Yudin +2 more
doaj +1 more source
Akt1 regulates pulmonary fibrosis via modulating IL-13 expression in macrophages
Innate Immunity, 2019 Idiopathic pulmonary fibrosis is a progressive interstitial pneumonia characterised by fibroblast accumulation, collagen deposition and extracellular matrix (ECM) remodelling.
Yunjuan Nie +7 more
doaj +1 more source
Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]
, 2010 Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica +8 more
core +1 more source
TGF-β1: Gentlemanly orchestrator in idiopathic pulmonary fibrosis (Review)
International Journal of Molecular Medicine, 2021 Idiopathic pulmonary fibrosis (IPF) is a worldwide disease characterized by the chronic and irreversible decline of lung function. Currently, there is no drug to successfully treat the disease except for lung transplantation.
Zhimin Ye, Yongbin Hu
semanticscholar +1 more source
A review of current studies on cellular and molecular mechanisms underlying pulmonary fibrosis induced by chemicals [PDF]
Environmental Health and Toxicology, 2018 Several studies showed that the inflammatory and fibrotic responses induced by polyhexamethylene guanidine phosphate (PHMG-p) were similar to those observed for idiopathic pulmonary fibrosis in South Korea in 2011.
Ha Ryong Kim +2 more
doaj +1 more source
Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]
, 2019 BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida +16 more
core +3 more sources
Pirfenidone for Idiopathic Pulmonary Fibrosis and Beyond
Cardiac failure review, 2022 Pirfenidone (PFD) slows the progression of idiopathic pulmonary fibrosis (IPF) by inhibiting the exaggerated fibrotic response and possibly through additional mechanisms, such as anti-inflammatory effects.
Alberto Aimo +10 more
semanticscholar +1 more source
International Journal of Occupational Medicine and Environmental Health, 2017 Objectives: Idiopathic pulmonary fibrosis (IPF) (J84.1 by the International Statistical Classification of Diseases and Related Health Problems, 10th revision – ICD-10) is a rare disease of unknown cause.
Ewa Niewiadomska +2 more
doaj +1 more source