Results 41 to 50 of about 999,769 (295)
Akt1 regulates pulmonary fibrosis via modulating IL-13 expression in macrophages
Innate Immunity, 2019 Idiopathic pulmonary fibrosis is a progressive interstitial pneumonia characterised by fibroblast accumulation, collagen deposition and extracellular matrix (ECM) remodelling.
Yunjuan Nie +7 more
doaj +1 more source
Diagnostic value of combining high resolution computed tomography with pulmonary artery systolic pressure for assessment of idiopathic pulmonary fibrosis [PDF]
Minia Journal of Medical ResearchBackground and objective: Idiopathic interstitial pneumonias (IIPs) are a heterogeneous group of non-neoplastic disorders resulting from the deterioration of lung tissue.
Alyaa Ali +3 more
doaj +1 more source
A review of current studies on cellular and molecular mechanisms underlying pulmonary fibrosis induced by chemicals [PDF]
Environmental Health and Toxicology, 2018 Several studies showed that the inflammatory and fibrotic responses induced by polyhexamethylene guanidine phosphate (PHMG-p) were similar to those observed for idiopathic pulmonary fibrosis in South Korea in 2011.
Ha Ryong Kim +2 more
doaj +1 more source
Cellular and Molecular Mechanisms in Idiopathic Pulmonary Fibrosis
Advances in Respiratory Medicine, 2023 Highlights What are the main findings? We reviewed the latest advances in aberrant molecular events and pathological alterations in different cell populations in idiopathic pulmonary fibrosis.
Yihang Zhang, Jia-Zhen Wang
semanticscholar +1 more source
Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E-2 production [PDF]
, 2004 Levels of prostaglandin E-2 (PGE(2)), a potent inhibitor of fibroblast function, are decreased in the lungs of patients with pulmonary fibrosis, which has been shown to be because of limited expression of cyclooxygenase-2 (COX-2).
McAnulty, R J +35 more
core +1 more source
PLoS ONE, 2022 IntroductionInflammatory bowel disease is a relapsing chronic gastrointestinal inflammatory disease. Idiopathic pulmonary fibrosis is a rare but serious extraintestinal pulmonary manifestation of inflammatory bowel disease.
Jiali Wang +7 more
doaj +1 more source
Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis.
New England Journal of Medicine, 2022 BACKGROUND Phosphodiesterase 4 (PDE4) inhibition is associated with antiinflammatory and antifibrotic effects that may be beneficial in patients with idiopathic pulmonary fibrosis.
L. Richeldi +9 more
semanticscholar +1 more source
Diffuse pulmonary hemosiderosis after exposure to pesticides - A case report [PDF]
, 1998 This report describes the clinical, radiological, microscopical and ligandohistochemical findings in a 17-year-old woman who suffered from an acute onset of pulmonary hemosiderosis after inhalation of pesticides used for the cultivation of strawberries ...
Kayser, Klaus +5 more
core +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
AntioxidantsOxidative stress in the human lung is caused by both internal (e.g., inflammation) and external stressors (smoking, pollution, and infection) to drive pathology in a number of lung diseases.
Corinne Hamblet +10 more
doaj +1 more source