Results 71 to 80 of about 105,026 (290)

Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension. [PDF]

, 2015
Pulmonary arterial hypertension (PAH) can be idiopathic or secondary to autoimmune diseases, and it represents one of the most threatening complications of systemic sclerosis (SSc).
Alessandri, Cristiano, Badagliacca, Roberto, Pendolino, Monica, Poscia, Roberto, Riccieri, Valeria, Sciarra, Iliana, Stefanantoni, Katia, Valesini, Guido, Vasile, M, Vizza, Carmine Dario   +9 more
core   +2 more sources

IPF - Idiopathic Pulmonary Fibrosis [PDF]

Breathe, 2019
Idiopathic pulmonary fibrosis or IPF is a long-term (chronic) lung disease. IPF is part of a large group of diseases that cause scarring of the lungs (this is called fibrosis). The diseases that cause scarring of the lungs are called interstitial lung diseases (ILD).
openaire   +2 more sources

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Diabetic Pneumopathy–A New Diabetes-Associated Complication: Mechanisms, Consequences and Treatment Considerations

Frontiers in Endocrinology, 2021
Patients with diabetes are over-represented among the total cases reported with “idiopathic” pulmonary fibrosis (IPF). This raises the question, whether this is an association only or whether diabetes itself can cause pulmonary fibrosis.
Stefan Kopf, Stefan Kopf, Varun Kumar, Varun Kumar, Varun Kumar, Zoltan Kender, Zoltan Kender, Zhe Han, Thomas Fleming, Thomas Fleming, Stephan Herzig, Stephan Herzig, Stephan Herzig, Peter P. Nawroth, Peter P. Nawroth, Peter P. Nawroth   +15 more
doaj   +1 more source

99mTc-MIBI Lung Scintigraphy in the Assessment of Pulmonary Involvement in Interstitial Lung Disease and Its Comparison With Pulmonary Function Tests and High-Resolution Computed Tomography: A Preliminary Study [PDF]

, 2015
The differentiation of active inflammatory processes from an inactive form of the disease is of great value in the management of interstitial lung disease (ILD).
Assadi, M., Bahtouee, M., Eftekhari, M., Javadi, H., Nabipour, I., Raeisi, A., Saberifard, J.   +6 more
core   +2 more sources

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Idiopathic pulmonary fibrosis - problematic rare lung disease. Pathogenesis, diagnosis, treatment and prognosis

Journal of Education, Health and Sport, 2022
Introduction: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal lung disease most often affecting people over the age of 50. Causes and pathogenesis of the disease are not fully understood.
Aleksander Kłos, Justyna Szydłowska, Olga Żuchnik, Olgierd Król, Piotr Kwiatkowski, Beata Kuczyńska, Magdalena Czelej, Konrad Gładysz, Krzysztof Gieroba, Marcin Szydłowski   +9 more
doaj   +1 more source

Einfluss der Art der Materialgewinnung auf die Diagnosefindung in der Lungenpathologie [PDF]

, 2019
Das Ziel der Arbeit ist die Darstellung der Möglichkeiten der Kryobiopsien für die Diagnostik von Lungenerkrankungen und Pleuraerkrankungen. Es wurde zunächst gezeigt, dass die transbronchialen Kryobiopsien einen deutlichen morphologischen Unterschied ...
Griff, Sergej
core   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

Norman Julius Zabusky OBITUARY [PDF]

, 2018
Norman Julius Zabusky, who laid the foundations for several critical advancements in nonlinear science and experimental mathematics, died of idiopathic pulmonary fibrosis on 5 February 2018 in Beersheba, Israel.
Campbell, David K., Newell, Alan C., Porter, Mason A.   +2 more
core   +1 more source