Results 71 to 80 of about 195,645 (350)

Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis

Cellular and Molecular Life Sciences, 2020
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an abnormal fibrotic response involving vast areas of the lungs.
T. Phan, P. Paliogiannis, Gheyath K Nasrallah, R. Giordo, A. Eid, A. Fois, A. Zinellu, A. Mangoni, G. Pintus   +8 more
semanticscholar   +1 more source

Smoking and Idiopathic Pulmonary Fibrosis [PDF]

Pulmonary Medicine, 2012
Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology with considerable morbidity and mortality. Cigarette smoking is one of the most recognized risk factors for development of IPF. Furthermore, recent work suggests that smoking may have a detrimental effect on survival of patients with IPF.
Chad K. Oh, Lynne A. Murray, Nestor A. Molfino   +2 more
openaire   +4 more sources

Rethinking Idiopathic Pulmonary Fibrosis

Clinics in Chest Medicine, 2021
Idiopathic pulmonary fibrosis (IPF) is a devastating disease for patients and their loved ones. Since initial efforts to characterize this disease in the 1960s, understanding of IPF has evolved considerably. Such evolution has continually challenged prior diagnostic and treatment paradigms, ushering in an era of higher confidence diagnoses with less ...
Oldham, Justin M, Vancheri, Carlo
openaire   +3 more sources

Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression. [PDF]

, 2019
Targeting activated fibroblasts, including myofibroblast differentiation, has emerged as a key therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF).
Chen, Ching-Hsien, Last, Jerold A, Li, Ji-Min, Oldham, Justin, Phan, Sem H, Wu, Reen, Xu, Jihao, Yang, David C   +7 more
core   +2 more sources

Diabetes Mellitus Contributes to Idiopathic Pulmonary Fibrosis: A Review From Clinical Appearance to Possible Pathogenesis

Frontiers in Public Health, 2020
Diabetes mellitus is a systematic metabolic disease characterized by persistent hyperglycemia, which complications often involve multiple organs and systems including vessels, kidneys, retinas, and nervous system.
Dongguang Wang, Yao Ma, Xiang Tong, Yonggang Zhang, Hong Fan   +4 more
doaj   +1 more source

Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis [PDF]

Терапевтический архив, 2018
The results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim.
V D Beketov, M V Lebedeva, N A Mukhin, A G Serova, A B Ponomarev, E N Popova, A Sh Yanakaeva, V A Solomka, A V Kondrashov, D V Konovalov   +9 more
doaj   +1 more source

Alveolar Epithelial Type II Cells as Drivers of Lung Fibrosis in Idiopathic Pulmonary Fibrosis

International Journal of Molecular Sciences, 2020
Alveolar epithelial type II cells (AT2) are a heterogeneous population that have critical secretory and regenerative roles in the alveolus to maintain lung homeostasis.
T. Parimon, C. Yao, B. Stripp, P. Noble, Peter Chen   +4 more
semanticscholar   +1 more source

Exacerbation of idiopathic pulmonary fibrosis [PDF]

Terapevticheskii arkhiv, 2020
Idiopathic pulmonary fibrosis (IPF) is usually characterized by a chronic and slowly progressive course. According to several studies, a small number of patients with IPF (about 515%) develops an acute deterioration of deasese exacerbation of IPF. Exacerbations of IPF can occur at any time of the disease and sometimes becomes the first manifestation ...
S. N. Avdeev, V. V. Gaynitdinova, Z. M. Merzhoeva, G. V. Neklyudova, N. A. Tsareva, G. S. Nuralieva   +5 more
openaire   +4 more sources

Efficacy and safety of Jin-shui Huan-xian granule for idiopathic pulmonary fibrosis: study protocol for a multicenter, randomized, double-blind, placebo-controlled trial

Trials, 2022
Background and rationale Idiopathic pulmonary fibrosis is a critical disease with a poor prognosis. Although different studies have been conducted for the treatment of idiopathic pulmonary fibrosis, limited treatments are available.
Shu-guang Yang, Xue-qing Yu, Jian-sheng Li, Yang Xie, Wei Zhang, Chengjun Ban, Jihong Feng, Lei Wu, Xuechao Lu, Limin Zhao, Yong Meng, Miao Zhou, Yong He, Weixian Luo   +13 more
doaj   +1 more source

Pathogenesis of Idiopathic Pulmonary Fibrosis [PDF]

Annual Review of Pathology: Mechanisms of Disease, 2014
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with aging that is characterized by the histopathological pattern of usual interstitial pneumonia. Although an understanding of the pathogenesis of IPF is incomplete, recent advances delineating specific clinical and pathologic features of IPF have led to better ...
Wolters, Paul J, Collard, Harold R, Jones, Kirk D   +2 more
openaire   +6 more sources