Results 181 to 190 of about 6,804 (215)
Some of the next articles are maybe not open access.
Idiopathic short stature: Management and growth hormone treatment
Growth Hormone & IGF Research, 2008In the management of ISS auxological, biochemical, psychosocial and ethical elements have to be considered. In boys with constitutional delay of growth and puberty androgens are effective in increasing height and sexual characteristics, but adult height is unchanged.
Alan D. Rogol +7 more
openaire +3 more sources
Growth Hormone Use in Children with Idiopathic Short Stature
Annals of Pharmacotherapy, 2004OBJECTIVE: To review the indication, pharmacology, pharmacokinetics, efficacy, and adverse effects of recombinant human growth hormone in children with idiopathic short stature (ISS). DATA SOURCES: A MEDLINE search (1966–December 2003) was performed using the key words human growth hormone, somatropin, Humatrope, normal children, somatrem, and ...
Milap C. Nahata, Karen L. Weise
openaire +3 more sources
Treatment of children and adolescents with idiopathic short stature
Nature Reviews Endocrinology, 2013Idiopathic short stature (ISS) is defined as shortness in childhood without a specific cause. ISS may be familial or nonfamilial and may be associated with or without delay of pubertal development. Treatment can be considered in an attempt to reduce the psychological burden caused by short stature in childhood and adult life.
openaire +3 more sources
Hormonal Treatment of Idiopathic Short Stature
Hormone Research in Paediatrics, 2007<i>Background and Objective:</i> The classification idiopathic short stature (ISS) represents a heterogeneous group of children who, as a group, are similar in height to patients with growth hormone (GH) deficiency, Turner syndrome, and short stature as a consequence of being born small for gestational age.
openaire +2 more sources
Should We Treat Children with Idiopathic Short Stature?
Hormone Research in Paediatrics, 1999The use of growth hormone (GH) to treat short children who are clearly GH-deficient is now well accepted. However, GH treatment of short children who have no currently recognizable abnormalities in their GH-insulin-like growth factor I axis remains controversial. Whether such children with so-called idiopathic short stature (ISS) should be treated with
Kerstin Albertsson-Wikland +4 more
openaire +3 more sources
Growth Hormone Treatment of Idiopathic Short Stature
Hormone Research, 1996Considerable controversy exists about the use of growth hormone (GH) treatment in short children without classical GH deficiency (idiopathic short stature or ISS). ISS is a multifactorial disorder with many potential causes rather than a single diagnostic entity, and it is in essence a diagnosis of exclusion.
openaire +3 more sources
Growth Hormone Treatment for Idiopathic Short Stature.
Pediatric endocrinology reviews : PER, 2018ISS is the commonest cause of short stature and poor growth and is arbitrarily defined as a height < -2 SDS without an identified cause. ISS consists largely of normal children with the remainder unrecognised conditions, mainly syndromes and genetic (monogenic and polygenic) causes.
Wayne S. Cutfield, Benjamin B. Albert
openaire +2 more sources
Zinc deficiency in Japanese children with idiopathic short stature
Journal of Pediatric Endocrinology and Metabolism, 2019Abstract Background and methods We investigated the frequency of zinc deficiency in Japanese children with idiopathic short stature, and evaluated whether serum zinc levels correlated with background factors, including age and standard deviation scores (SDSs) for height and serum insulin-like growth ...
Kei Yoshida +3 more
openaire +3 more sources
Auxological Criteria for Treating Children with Idiopathic Short Stature
Hormone Research in Paediatrics, 2011Children with idiopathic short stature (ISS) may not reach an adult height within their genetic target. In 2003, the United States Food and Drug Administration approved biosynthetic growth hormone (GH) for the treatment of children with ISS whose heights exceeded 2.25 standard deviation scores below the mean and who were considered unlikely to reach a ...
openaire +2 more sources
Growth hormone in children with idiopathic short stature
BMJ, 2011The dose should be tailored to individual responsiveness to optimise growth and minimise ...
openaire +2 more sources