Results 171 to 180 of about 12,816 (223)

Idiopathic Thrombocytopenic Purpura

Postgraduate Medicine, 1962
The acute form of ITP may be drug-induced or may follow infection or exposure to chemicals. The chronic form represents a self-perpetuating immunologic (auto-immune) disorder, at times associated with chronic lymphatic leukemia and other disorders. In some cases, it may be a prodrome of systemic lupus, to which it seems to be closely related.
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Idiopathic Thrombocytopenic Purpura

Primary Care: Clinics in Office Practice, 1980
The finding of thrombocytopenia with normal or increased megakaryocytes on bone marrow aspirate supports the diagnosis of ITP. It is essential, however, that every effort be made to exclude other causes of the consumption of platelets. Most cases of chronic ITP are immune in origin; consequently, steroid therapy is the initial treatment of choice ...
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Idiopathic Thrombocytopenic Purpura

Archives of Internal Medicine, 1986
To the Editor. —There is more evidence that genetic factors predispose to chronic immunologic thrombocytopenic purpura (ITP) than is summarized by Bogart and Wittels in their article on ITP in two elderly siblings in the December 1985 issue of theArchives.
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Idiopathic Autoimmune Thrombocytopenic Purpura

Advances in Pediatrics, 1994
Childhood ITP occurs in acute and chronic forms. In general, both diseases are mild and can be managed conservatively. Approaches to therapy are highly controversial and vary widely among pediatricians and academic centers. Approximately 5% of children with ITP will develop chronic disease with severe thrombocytopenia and bleeding.
J, Kurtzberg, J A, Stockman
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Idiopathic thrombocytopenic purpura

Current Paediatrics, 1995
Idiopathic thrombocytopenic purpura in children usually a self limiting disorder. It may follow a viral infection or immunisation and is caused by an inappropriate response of the immune system. About 20-30% of children will fail to remit over six months (chronic idiopathic thrombocytopenic purpura).
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Idiopathic Thrombocytopenic Purpura

New England Journal of Medicine, 1966
A CHANGE in the concepts regarding idiopathic thrombocytopenic purpura has occurred during the past fifteen years mainly because of the recognition of three important facts: The thrombocytopenia is the result of increased platelet destruction. The old hypothesis, originally postulated by Frank,1 , 2 of a toxic depression of megakaryocytes and their ...
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Infantile Idiopathic Thrombocytopenic Purpura

Pediatric Hematology and Oncology, 1990
Idiopathic thrombocytopenic purpura (ITP) in childhood is a benign disease, as only 10% to 20% of the patients have a chronic course. A retrospective study of 57 ITP patients ranging in age from four months to two years revealed that 30% of them proceeded to chronicity.
A, Ballin, G, Kenet, H, Tamary, G, Rechavi, G, Chividalli, Y, Burstein, T, Tauber, M, Nussinovitch, D, Meytes   +8 more
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Idiopathic Thrombocytopenic Purpura in Children

Seminars in Thrombosis and Hemostasis, 2008
ITP in childhood is most often of the acute, self-limited variety, with spontaneous recovery occurring within a matter of days or weeks. In many of these children, acute thrombopenic purpura follows in the wake of a viral infection. While the pathogenesis is not entirely clear, it seem probable that the platelet membrane is altered by virus or by ...
J M, Lusher, R, Iyer
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Idiopathic Thrombocytopenic Purpura in Pregnancy

Clinics in Perinatology, 1985
Idiopathic thrombocytopenic purpura (ITP) frequently occurs in young women, and is therefore encountered in pregnancy. Any woman with a history of ITP, regardless of her clinical status, has some risk of delivering a thrombocytopenic infant, since the antiplatelet antibodies cross the placenta. Methods for predicting which infants are at high risk, for
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Idiopathic Thrombocytopenic Purpura in Adults

Journal of Pediatric Hematology/Oncology, 2003
Immune thrombocytopenic purpura (ITP) is an organ-specific autoimmune disorder in which platelets opsonized by antiplatelet antibodies are destroyed by the reticuloendothelial system. As a result the peripheral blood platelet count is low; if sufficiently severe, it may lead to bruising and mucocutaneous bleeding.
Drew, Provan, Adrian, Newland
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