Results 181 to 190 of about 12,816 (223)
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Thrombokinetics in Idiopathic Thrombocytopenic Purpura*
British Journal of Haematology, 1970Summary Measurements of platelet production in 16 patients with idiopathic thrombocytopenic purpura (ITP) demonstrate that megakaryocytopoiesis (total thrombopoiesis) and platelet turnover (effective thrombopoiesis) are increased in parallel to as much as 8 times normal. The marrow megakaryocytes show changes characteristic of stimulated thrombopoiesis.
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Idiopathic Thrombocytopenic Purpura in Adults
Southern Medical Journal, 1988Idiopathic thrombocytopenic purpura (ITP) is a primary immune thrombocytopenia that is typically manifested in adults by acute bleeding, severe thrombocytopenia, and normal to increased megakaryocytes in the bone marrow. Labeling studies suggest that most patients with ITP have an IgG antibody directed against the platelet membrane resulting in ...
D P, Brannan, T H, Guthrie
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Treatment of Idiopathic Thrombocytopenic Purpura
Hospital Practice, 1983ITP is a common disease that is sorely in need of better management. Treatment strategy requires consideration of both long-term benefits and long-term hazards of each available therapeutic option. This discussion reviews conventional therapy as well as newer approaches to refractory ITP, including immunosuppressants, vinca alkaloids, colchicine ...
W J, Harrington +5 more
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Management of idiopathic thrombocytopenic purpura
The Indian Journal of Pediatrics, 1998Idiopathic thrombocytopenic purpura is not an uncommon bleeding disorder with a prevalence of 40-80 per million children per year. Over the last six decades, the subject of ITP has attracted the attention of pediatricians and hematologists. It is one of the subjects which has many controversies because of its unpredictable course heralded by remission ...
V P, Choudhry, R, Kashyap, H P, Pati
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Splenectomy for Idiopathic Thrombocytopenic Purpura
Archives of Surgery, 1966IDIOPATHIC thrombocytopenic purpura (ITP) is a disease entity characterized by a decrease in the circulating platelets despite an increase in megakaryocytes seen in the marrow. There is a concomitant bleeding tendency, but the precise pathophysiological cause or etiology is unknown.
G E, Block, R, Evans, R, Zajtchuk
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Idiopathic Thrombocytopenic Purpura in Children
The Nurse Practitioner, 1987Idiopathic thrombocytopenic purpura is a disorder characterized by antibody-mediated platelet destruction. Other than thrombocytopenia and its consequences, the physical and laboratory examination of the child with ITP is normal. The prognosis in children is excellent; 90 percent will recover spontaneously within one year.
G A, Thomas, R T, O'Brien
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Familial idiopathic thrombocytopenic purpura
The Journal of Pediatrics, 1963The unusual occurrence of idiopathic thrombocytopenic purpura in 4 brothers is described. The purpura appeared in early infancy and continued for 1 to 3 years until controlled by splenectomy. The thrombocytopenic purpura was not associated with any other blood dyscrasia, drug, toxin, platelet antibodies, or maternal antibodies.
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Myelofibrosis and idiopathic thrombocytopenic purpura
Annals of Hematology, 1997A case of idiopathic myelofibrosis (IMF) with concomitant autoimmune thrombocytopenic purpura (AITP) is reported. The literature on platelet antibodies in IMF is reviewed.
M A, Seelen +3 more
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Idiopathic thrombocytopenic purpura in a cat
Journal of the American Animal Hospital Association, 1999An 11-year-old, castrated, male domestic shorthair cat was presented for hematuria and pollakiuria. The cat had a marked thrombocytopenia, and a bone-marrow core biopsy demonstrated megakaryocytic hyperplasia with many megakaryocyte-associated neutrophils (i.e., emperipolesis). On peripheral blood, collected at initial presentation, what appeared to be
C L, Garon +3 more
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Idiopathic thrombocytopenic purpura in lymphoma
Cancer, 1976Five patients with idiopathic thrombocytopenic purpura (ITP) associated with malignant lymphoma are presented, and twelve other cases reported in the literature are reviewed. Thirteen patients (76%) had Hodgkin's disease; two had diffuse histiocytic, one, diffuse mixed lymphoma.
K, Fink, H, Al-Mondhiry
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