Results 81 to 90 of about 112,361 (357)
Conceptualization of Idle (Laghw) and its Relation to Medical Futility
Journal of Medical Ethics and History of Medicine, 2016 A major debate in medical ethics is the request for futile treatment. The topic of medical futility requires discrete assessment in Iran for at least two reasons.
Mohsen Rezaei Adaryani +4 more
doaj
Advanced Science, EarlyView.The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang +12 more
wiley +1 more source
Advanced Science, EarlyView.This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He +13 more
wiley +1 more source
Advanced Science, EarlyView.Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao +11 more
wiley +1 more source
Acta Scientiarum: Animal Sciences, 2008 O presente trabalho teve por objetivo avaliar o consumo e comportamento ingestivo de caprinos e ovinos alimentados com palma Gigante (Opuntia ficus-indica Mill) e palma Orelhade-elefante (Opuntia sp.).
Agenor Costa Ribeiro Neto +5 more
doaj
A Collaborative CPU Vector Offloader: Putting Idle Vector Resources to Work on Commodity Processors [PDF]
, 2021 Youngbin Son +6 more
openalex +1 more source
Advanced Science, EarlyView.Uncovering a new layer of translational control, this study reveals how TRMT6/TRMT61A‐mediated tRNA‐m1A methylation drives pro‐tumorigenic senescence in colorectal cancer. By selectively enhancing ARG2 translation, this epitranscriptomic axis triggers an NF‐κB‐dependent SASP.
Tuoyang Li +17 more
wiley +1 more source
Advanced Science, EarlyView.We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li +10 more
wiley +1 more source
High‐Rate Cross‐Channel Entanglement Swapping Between Independent On‐Chip Sources
Advanced Science, EarlyView.To interconnect individual chip‐based quantum sources, high‐performance entanglement swapping is indispensable. Here, using low‐loss silicon chips with waveguide structure and frequency‐offset pumps, this work demonstrates high‐rate cross‐channel entanglement swapping.
Haoyang Wang +5 more
wiley +1 more source