Results 1 to 10 of about 91,246 (333)
Multivalent IDP assemblies: Unique properties of LC8‐associated, IDP duplex scaffolds [PDF]
FEBS Letters, 2015 A wide variety of subcellular complexes are composed of one or more intrinsically disordered proteins (IDPs) that are multivalent, flexible, and characterized by dynamic binding of diverse partner proteins. These multivalent IDP assemblies, of broad functional diversity, are classified here into five categories distinguished by the number of IDP chains
Clare Woodward +3 more
semanticscholar +6 more sources
The Amazing World of IDPs in Human Diseases [PDF]
Biomolecules, 2021 It has been clearly established that some proteins or protein regions are devoid of any stable secondary and/or tertiary structure under physiological conditions, but still possess fundamental biological functions [...]
Monti, Simona Maria +2 more
openaire +5 more sources
Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics
Proteins: Structure, Function, and Bioinformatics, EarlyView., 2023 Abstract Before the controversial approval of humanized monoclonal antibody lecanemab, which binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for Alzheimer's disease (AD) were symptomatic. The researchers are still struggling to find a breakthrough in AD therapeutic medicine, which is partially attributable to lack in ...
Sharif Arar +2 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView., 2023 Abstract Among the various factors controlling the amyloid aggregation process, the influences of ions on the aggregation rate and the resulting structures are important aspects to consider, which can be studied by molecular simulations. There is a wide variety of protein force fields and ion models, raising the question of which model to use in such ...
Eva Smorodina +3 more
wiley +1 more source
Vis–NIR Reflectance Microspectroscopy of IDPs [PDF]
The Planetary Science Journal, 2020 Abstract Visible near-infrared (Vis–NIR) reflectance spectroscopy is a powerful nondestructive technique allowing the parent bodies identification of cosmomaterials such as meteorites, micrometeorites, and interplanetary dust particles (IDPs) studied in the laboratory.
Maupin, Romain +5 more
openaire +3 more sources
A specification for IdP hinting
, 2021 This document defines a generic browser-based protocol for conveying - to services - hints about the IdPs or SP-IdP-proxies that should be used for authenticating the principal. This protocol, colloquially referred to as Identity Provider (IdP) hinting, can greatly simplify the discovery process for the end-user, by enabling entities to produce and ...
AARC Community Members, AppInt Members
openaire +2 more sources
Islam and The Plight of Internally Displaced Persons (IDPS) In IDP Camps in Abuja, Nigeria
Al-Mada: Jurnal Agama, Sosial, dan Budaya, 2021 The paper is based on a study conducted on the Plight of Internally Displaced Persons (IDPs) in Abuja, Federal Capital Territory, Nigeria. The study sought to find out the socio-economic and psychological conditions of three IDP camps in Durumi, Karmajiji and Dakwa, and the extent of state and non-state actors support to the camps.
Seleiman B Mohammad, Rafatu Abdulhamid
openaire +3 more sources
Predicting the Predictive Power of IDP Ensembles [PDF]
Structure, 2014 The function of intrinsically disordered proteins may be interpreted in terms of their structural ensembles. The article by Schwalbe and colleagues in this issue of Structure combines NMR and SAXS constraints to generate structural ensembles that unveil important functional and pathological features.
Mihaly Varadi, Peter Tompa, Peter Tompa
openaire +4 more sources
R-IDPS: Real Time SDN-Based IDPS System for IoT Security
Computers, Materials & Continua, 2022 The advent of the latest technologies like the Internet of things (IoT) transforms the world from a manual to an automated way of lifestyle. Meanwhile, IoT sector open numerous security challenges. In traditional networks, intrusion detection and prevention systems (IDPS) have been the key player in the market to ensure security.
Mazhar, Noman +5 more
openaire +1 more source
Intrinsically Disordered Peptide Nanofibers from a Structured Motif Within Proteins
Angewandte Chemie, EarlyView.The sequence (PQYQP), derived from the SRC protein, was combined with the self‐assembly motif (Nap‐FF) to produce intrinsically disordered peptide (IDP) assemblies that form cell‐compatible hydrogels via enzyme‐instructed self‐assembly (EISA). Abstract Intrinsically disordered regions (IDRs) are ubiquitous in proteins, orchestrating complex cellular ...
Yuchen Qiao +7 more
wiley +2 more sources