Results 151 to 160 of about 80,391 (300)
Brain Imaging Phenotypes Associated with Polygenic Risk for Essential Tremor
Abstract Essential tremor (ET) is a common movement disorder with a strong genetic basis. Magnetic resonance imaging (MRI), particularly diffusion‐weighted MRI (dMRI) and T1 MRI, have been used to identify brain abnormalities of ET patients. However, the mechanisms by which genetic risk affects the brain to render individuals vulnerable to ET remain ...
Miranda Medeiros+14 more
wiley +1 more source
Imidacloprid Uptake and Leaching in the Critical Root Zone of a Florida Entisol
Imidacloprid (IDP) products are applied via soil drenching in the citrus critical root zone (CCRZ) at 0–60 cm soil depth. This study aimed to determine the uptake and leaching of IDP in the CCRZ of a Florida Entisol. The treatments include: (1) a control
Qudus O. Uthman+5 more
doaj +1 more source
Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang+4 more
wiley +1 more source
Abstract Transcription factors carry long intrinsically disordered regions often containing multiple activation domains. Despite numerous recent high‐throughput identifications and characterizations of activation domains, the interplay between sequence motifs, activation domains, and regulator binding in intrinsically disordered transcription factor ...
Amanda D. Due+10 more
wiley +1 more source
Learning from local economic development experiences: Observations on Integrated Development Programmes of the Free State, Republic of South Africa [PDF]
The aim of this paper is to assess the degree to which the components of the Rural Economic and Enterprise Development (REED) framework have been incorporated into integrated development planning (IDP) or into strategic local economic development (LED ...
Davis, Junior
core +1 more source
Afghanistan consults on an IDP policy
A recent commitment announced by the government of Afghanistan to develop a national policy on internal displacement is timely. If carried out well in the lead-up to transition, it will help the government to better protect and meet the needs of internally displaced communities across the country.
Schrepfer, N, Tyler, D
openaire +2 more sources
Polyglutamine expansion induced dynamic misfolding of androgen receptor
Abstract Spinal bulbar muscular atrophy (SBMA) is caused by a polyglutamine expansion (pQe) in the N‐terminal transactivation domain of the human androgen receptor (AR‐NTD), resulting in a combination of toxic gain‐ and loss‐of‐function mechanisms. The structural basis of these processes has not been resolved due to the disordered nature of the NTD ...
Laurens W. H. J. Heling+10 more
wiley +1 more source
A Novel and Simple Invariant-Domain-Preserving Framework for PAMPA Scheme: 1D Case [PDF]
The PAMPA (Point-Average-Moment PolynomiAl-interpreted) method, proposed in [R. Abgrall, Commun. Appl. Math. Comput., 5: 370-402, 2023], combines conservative and non-conservative formulations of hyperbolic conservation laws to evolve cell averages and point values.
arxiv
Equilibrium condensation from chondritic porous IDP enriched vapor: Implications for Mercury and enstatite chondrite origins [PDF]
D. S. Ebel, C. M. O'd. Alexander
openalex +1 more source