Results 31 to 40 of about 10,067 (226)

Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

Biomolecules, 2021
Motifs within proteins help us categorize their functions. Intrinsically disordered proteins (IDPs) are rich in short linear motifs, conferring them many different roles.
Estella A. Newcombe, Catarina B. Fernandes, Jeppe E. Lundsgaard, Inna Brakti, Kresten Lindorff-Larsen, Annette E. Langkilde, Karen Skriver, Birthe B. Kragelund   +7 more
doaj   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

Advanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg, Anastasia Lopatina, Hao Ruan, Tom Scheidt, Simone Mosna, Emre Pekbilir, Julia Bieber, Frank Schäfer‐Depoix, Katharina Landfester, Carla Schmidt, Martin M. Möckel, Svenja Morsbach, Friederike Schmid, Dorothee Dormann, Lukas Stelzl, Martin Girard, Edward A. Lemke   +16 more
wiley   +1 more source

Social Cohesion Between Internally Displaced People and Host Communities in Somali Region of Ethiopia: The Case of Qolaji Camp

Journal of Arts, Humanities and Social Science
In the Qoloji settlement in the Somali region of Ethiopia, this study examines the social cohesion between the host community and internally displaced people (IDPs). The study uses a mixed-methods descriptive approach that includes two focus groups, nine
Kader Ahmed Abdulahi
doaj   +1 more source

A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

Advanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels, Joana Caria, Edward A. Lemke   +2 more
wiley   +1 more source

Determinants of Exclusive Breastfeeding for the First 6 Months Among Children Under Five in Internally Displaced Persons Camps in Eastern Democratic Republic of Congo; a Cross-Sectional Study. [PDF]

Public Health Chall
Eastern Democratic Republic of Congo's IDPs camps in Goma have very few mothers who are exclusively breastfeeding their children, which is less than half of what is considered the standard by both national and international guidelines. ABSTRACT Introduction Giving only breast milk in the first 6 months lowers the chances of childhood diseases and death.
Kashafali A, Aizeque A, Shams Z, Farhan K, Alhassan A, Ahmad B, Mufungizi I, Odonkor FO, Kihanduka E, Tague C, Wei CR, Rhugendabanga F, Bavurhe RF, Cakirwa H, Balagizi F, Akilimali A, Zihindula F, Kanda MS, Langat AK, Medical Research Circle (MedReC) Collaborators.   +19 more
europepmc   +2 more sources

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

STRATEGIC PRIORITIES FOR THE INTERNAL MIGRATION PROCESSES REGULATION IN UKRAINE [PDF]

Baltic Journal of Economic Studies, 2018
As the result of the annexation of the Crimea and Donbass military conflict, there was an emergence of forced migration. It ought to be emphasized that today issues related to addressing problems of internally displaced persons (IDPs), are relevant and ...
Olga Balueva, Elena Chuprina
doaj   +1 more source

Gate‐Tunable Polarity‐Reconfigurable Photovoltaic Response With Dual Linearity in NbS3/WSe2 Heterostructures for In‐Sensor Image Processing

Advanced Science, EarlyView.
An NbS3/WSe2 van der Waals heterostructure realizes a continuously gate‐tunable self‐powered photovoltaic response through interfacial band‐alignment modulation and reversible built‐in electric‐field switching. The short‐circuit photocurrent scales linearly with incident power density, while short‐circuit photoresponsivity varies linearly with gate ...
Jidong Liu, Jianxiong Xie, Qiaoyan Hao, Yutao Hu, Zhen He, Haolin Liu, Danting Lin, Haibo Gan, Yudi Tu, Wenjing Zhang   +9 more
wiley   +1 more source

ASCORBIC ACID STATUS IN DIFFERENT POPULATION CATEGORIES DURING THE RUSSIAN-UKRAINIAN WAR

Проблеми екології та медицини
Our study aimed to examine the ascorbic acid (AA) status of the Ukrainian population during wartime conditions. Ascorbic acid is one of the most essential vitamins in human nutrition.
N.D. Gerasymenko, Ya.M. Avramenko, O.V. Bielan, A.V. Lavrenko, I.A. Mormol, I.P. Kaidashev   +5 more
doaj   +1 more source

Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins

Advanced Science, EarlyView.
Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller, Cheryl Hayashi, Thomas R. Scheibel   +2 more
wiley   +1 more source