Results 101 to 110 of about 190,232 (322)
IDE Gene Polymorphism Influences on BPSD in Mild Dementia of Alzheimer's Type [PDF]
Current Gerontology and Geriatrics Research, 2008 Insulin degrading enzyme (IDE) degrades amyloid (A), which may inhibit the accumulation of A in a brain affected with dementia of Alzheimer's type (DAT). A decrease in the activity of IDE results in changes in glucose utilization in the brain, which could affect the cognitive and psychiatric symptoms of DAT.
Sato, Noriko +4 more
openaire +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A-Lister: a tool for analysis of differentially expressed omics entities across multiple pairwise comparisons. [PDF]
, 2019 BackgroundResearchers commonly analyze lists of differentially expressed entities (DEEs), such as differentially expressed genes (DEGs), differentially expressed proteins (DEPs), and differentially methylated positions/regions (DMPs/DMRs), across ...
Listopad, Stanislav A +1 more
core +1 more source
convertid: Convert Gene IDs Between Each Other and Fetch Annotations from Biomart [PDF]
, 2021 Vidal Fey, Henrik Edgren
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Relationships of iduronic acid-2-sulfatase with metastasis and prognosis of colorectal cancer
Di-san junyi daxue xuebao, 2019 Objective To select lysosomal molecules related to metastasis and prognosis of colorectal cancer. Methods The clinical sample information and gene transcriptome sequencing expression matrix of colorectal cancer TCGA database (Colon Adenocarcinoma TCGA ...
YANG Zeyu +5 more
doaj +1 more source
Anterior Olfactory Nucleus [PDF]
, 2008 This report contains a gene expression summary of the anterior olfactory nucleus (AON), derived from the Allen Brain Atlas (ABA) in situ hybridization mouse data set.
Allen Institute for Brain Science +3 more
core +2 more sources
, 2011 BioMart recently got a facelift. I'm not sure if this was always available in the old BioMart, but there's now a link to a gene ID converter that worked pretty well for me for converting S. cerevisiae gene IDs to standard gene names. It looks like the tool will convert nearly any ID you could imagine.
openaire +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Reprogramming of lysosomal gene expression by interleukin-4 and Stat6. [PDF]
, 2013 BACKGROUND: Lysosomes play important roles in multiple aspects of physiology, but the problem of how the transcription of lysosomal genes is coordinated remains incompletely understood.
Bartlett, NW +9 more
core +2 more sources