Results 31 to 40 of about 190,232 (322)

Identity crisis? The need for systematic gene IDs [PDF]

Trends in Parasitology, 2011
Recent years have seen an explosion in the availability of protozoan pathogen genome sequences. Although data regarding the underlying genome sequence remain relatively stable after the initial draft, understanding of specific gene function is increasing rapidly.
Marilyn, Parsons, Peter J, Myler, Matthew, Berriman, David S, Roos, Kenneth D, Stuart   +4 more
openaire   +2 more sources

A Pathway Analysis Tool for Analyzing Microarray Data of Species with Low Physiological Information [PDF]

, 2008
Pathway information provides insight into the biological processes underlying microarray data. Pathway information is widely available for humans and laboratory animals in databases through the internet, but less for other species, for example, livestock.
Pas, M.F.W., te, Hemert, S., van, Hulsegge, B., Hoekman, A.J.W., Pool, M.H., Rebel, J.M.J., Smits, M.A.   +6 more
core   +3 more sources

Comparative analysis of plant immune receptor architectures uncovers host proteins likely targeted by pathogens. [PDF]

, 2016
BACKGROUND: Plants deploy immune receptors to detect pathogen-derived molecules and initiate defense responses. Intracellular plant immune receptors called nucleotide-binding leucine-rich repeat (NLR) proteins contain a central nucleotide-binding (NB ...
Cevik, Volkan, Dagdas, Gulay, Jones, Jonathan, Krasileva, Ksenia, Sarris, Panagiotis   +4 more
core   +11 more sources

HGPGD: the human gene population genetic difference database. [PDF]

PLoS ONE, 2013
Demographic events such as migration, and evolutionary events like mutation and recombination, have contributed to the genetic variations that are found in the human genome.
Yongshuai Jiang, Ruijie Zhang, Hongchao Lv, Jin Li, Miao Wang, Yiman Chang, Wenhua Lv, Xin Sheng, Jingjing Zhang, Panpan Liu, Jiajia Zheng, Miao Shi, Guiyou Liu   +12 more
doaj   +1 more source

CCR7-mediated T follicular helper cell differentiation is associated with the pathogenesis and immune microenvironment of spinal cord injury-induced immune deficiency syndrome

Frontiers in Neuroscience, 2022
Spinal cord injury-induced immune deficiency syndrome (SCI-IDS) is a disorder characterized by systemic immunosuppression secondary to SCI that dramatically increases the likelihood of infection and is difficult to treat.
Chaochen Li, Chaochen Li, Chaochen Li, Chunshuai Wu, Chunshuai Wu, Chunshuai Wu, Guanhua Xu, Yang Liu, Jiajia Chen, Jinlong Zhang, Hongxiang Hong, Chunyan Ji, Chunyan Ji, Chunyan Ji, Zhiming Cui, Zhiming Cui, Zhiming Cui   +16 more
doaj   +1 more source

HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions [PDF]

, 2012
Background: The modeling of interactions among transcription factors (TFs) and their respective target genes (TGs) into transcriptional regulatory networks is important for the complete understanding of regulation of biological processes.
Luiz A. Bovolenta, Marcio L. Acencio, Ney Lemke   +2 more
core   +4 more sources

Case report: a rare case of Hunter syndrome (type II mucopolysaccharidosis) in a girl

BMC Medical Genetics, 2019
Background Hunter syndrome (mucopolysaccharidosis type II) is a recessive X-linked disorder due to mutations in the iduronate 2-sulfatase (IDS) gene. The IDS gene encodes a lysosomal enzyme, iduronate 2-sulfatase. The disease occurs almost exclusively in
A. N. Semyachkina, E. Y. Voskoboeva, E. Y. Zakharova, E. A. Nikolaeva, I. V. Kanivets, A. D. Kolotii, G. V. Baydakova, M. N. Kharabadze, R. G. Kuramagomedova, N. V. Melnikova   +9 more
doaj   +1 more source

Wheat Disease Resistance Genes and Their Diversification Through Integrated Domain Fusions

Frontiers in Genetics, 2020
Plants are in a constant evolutionary arms race with their pathogens. At the molecular level, the plant nucleotide-binding leucine-rich repeat receptors (NLRs) family has coevolved with rapidly evolving pathogen effectors.
Ethan J. Andersen, Madhav P. Nepal, Jordan M. Purintun, Dillon Nelson, Glykeria Mermigka, Panagiotis F. Sarris, Panagiotis F. Sarris, Panagiotis F. Sarris   +7 more
doaj   +1 more source

Id genes in nervous system development.

Histology and histopathology, 2000
Id genes encode helix-loop-helix proteins that function to mediate processes important for normal development including cellular differentiation, proliferation and apoptosis. Id proteins act as negative regulators of other transcription factors, which are essential for cell determination and differentiation in diverse cell types, and interact with ...
Andres-Barquin, P.J., Hernandez, M.C., Israel, M.A.   +2 more
openaire   +3 more sources

Rodent BC1 RNA gene as a master gene for ID element amplification. [PDF]

Proceedings of the National Academy of Sciences, 1994
ID elements are short interspersed repetitive DNA elements (SINEs) which have amplified in rodent genomes via retroposition, a process involving an RNA intermediate. BC1, an abundant ID-related transcript, is transcribed from a conserved, single-copy gene in rodents.
J, Kim, J A, Martignetti, M R, Shen, J, Brosius, P, Deininger   +4 more
openaire   +2 more sources