Results 51 to 60 of about 2,703,511 (280)
Genome-wide identification of the NLR gene family in Haynaldia villosa by SMRT-RenSeq
BMC Genomics, 2022 Background Nucleotide-binding and leucine-rich repeat (NLR) genes have attracted wide attention due to their crucial role in protecting plants from pathogens.
Zhenpu Huang +11 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
IDS Postgraduate Prospectus 2020
, 2019 The Institute of Development Studies (IDS) is a global research and learning organisation for equitable and sustainable change. In partnership with the University of Sussex, IDS is ranked first in the world for development studies by the QS University ...
IDS (19281550)
core +1 more source
miRMut: Annotation of mutations in miRNA genes from human whole-exome or whole-genome sequencing
STAR Protocols, 2022 Summary: Here, we present the miRMut protocol to annotate mutations found in miRNA genes based on whole-exome sequencing (WES) or whole-genome sequencing (WGS) results.
Martyna O. Urbanek-Trzeciak +2 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 2017 This is a brochure to promote IDS' Masters courses in international development (http://www.ids.ac.uk/study)
IDS (19281550)
core +1 more source
Molecular Genetics and Metabolism Reports, 2020 We previously showed that the genotype-phenotype correlation in MPS II is well-conserved in Japan (Kosuga et al., 2016). Almost all of our patients with attenuated MPS II have missense variants, which is expected to result in residual activity of ...
Yasuyuki Fukuhara +9 more
doaj +1 more source
Expression of Id and ITF-2 genes in the mammary gland during pregnancy [PDF]
Biochemical and Biophysical Research Communications, 2008 Id-1 is one of the four related helix-loop-helix Id proteins that act as inhibitors of the basic helix-loop-helix (bHLH) transcription factors that control cell differentiation, development and carcinogenesis. We previously found that Id-1 regulated the growth, differentiation, apoptosis and invasion of mouse mammary epithelial cells in culture.
Yoko, Itahana +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
CRISPR/Cas9 Epigenome Editing Potential for Rare Imprinting Diseases: A Review
Cells, 2020 Imprinting diseases (IDs) are rare congenital disorders caused by aberrant dosages of imprinted genes. Rare IDs are comprised by a group of several distinct disorders that share a great deal of homology in terms of genetic etiologies and symptoms ...
Linn Amanda Syding +3 more
doaj +1 more source