Results 71 to 80 of about 2,908,134 (284)

Reciprocal Id Expression and Myelin Gene Regulation in Schwann Cells

Molecular and Cellular Neuroscience, 1999
Id proteins are thought to act as dominant negative antagonists of basic helix-loop-helix (bHLH) transcription factors that direct differentiation in various cell types. We found that Schwann cells express all four Id-family genes and that their transcript levels were reciprocally regulated in pairs during nerve maturation in vivo and cAMP-mediated ...
P, Thatikunta, W, Qin, B A, Christy, G I, Tennekoon, J L, Rutkowski   +4 more
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Transcriptome-informed identification and characterization of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes

iScience
Summary: Insect physiology and reproduction depend on several terpenoid compounds, whose biosynthesis is mainly unknown. One enigmatic group of insect monoterpenoids are mealybug sex pheromones, presumably resulting from the irregular coupling activity ...
Mojca Juteršek, Iryna M. Gerasymenko, Marko Petek, Elisabeth Haumann, Sandra Vacas, Kalyani Kallam, Silvia Gianoglio, Vicente Navarro-Llopis, Michael Heethoff, Ismael Navarro Fuertes, Nicola Patron, Diego Orzáez, Kristina Gruden, Heribert Warzecha, Špela Baebler   +14 more
doaj   +1 more source

BioMart Gene ID Converter

, 2011
BioMart recently got a facelift. I'm not sure if this was always available in the old BioMart, but there's now a link to a gene ID converter that worked pretty well for me for converting S. cerevisiae gene IDs to standard gene names. It looks like the tool will convert nearly any ID you could imagine. Looks like it will also map Affy probe IDs to gene,
openaire   +1 more source

RT-PCR gene primer sequences and probe IDs.

, 2014
RT-PCR gene primer sequences and probe IDs.
Andreas J. Bäumler (133812), Lauren A. Hirao (344043), Frank Chuang (622627), Ross Tarara (491053), Monsicha Somrit (622623), Anne N. Fenton (622625), Robert W. Crawford (133796), William K. Hu (452483), Chris A. Gaulke (622624), Satya Dandekar (61929), Maria L. Marco (153036), Olivier Bourry (249074), Sumathi Sankaran-Walters (253908), Holland Cheng (622628), Irina Grishina (61928), Jay A. Li (622626)   +15 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Protein-coding genes in humans and model mammals (mouse, rat and pig): gene identifiers and disambiguation of gene nomenclature retrieved from the Ensembl genome browser

BMC Genomics
Background Gene nomenclature contains current official symbols and various numbers of synonyms, which pose a challenge to integrating genomic data and increase the probability that different genes share the same symbol.
Grzegorz R. Juszczak, Chandra S. Pareek, Urszula Czarnik, Mariusz Pierzchała   +3 more
doaj   +1 more source

GEOGLE: context mining tool for the correlation between gene expression and the phenotypic distinction

BMC Bioinformatics, 2009
Background In the post-genomic era, the development of high-throughput gene expression detection technology provides huge amounts of experimental data, which challenges the traditional pipelines for data processing and analyzing in scientific researches.
Ping Jie, Ding Guohui, Li Yun, Zheng Siyuan, Tu Kang, Yu Yao, Hao Pei, Li Yixue   +7 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Conserved miRNAs IDs and predicted targets gene families.

, 2013
Conserved miRNAs IDs and predicted targets gene families.
Cristian Antonio Rojas (394931), Flávia Thiebaut (394930), Sabrina Rosario (394929), Adriana Silva Hemerly (189118), Paulo Cavalcanti Gomes Ferreira (189122), Clicia Grativol (222873), Laurent Farrineli (394932), Mariana Carnavale Bottino (394928)   +7 more
core   +1 more source