Results 111 to 120 of about 97,768,729 (189)

A ZEBRATISH IDURONATE-2-SULFATASE CANDIDATE ORTHOLOGUE IS STRONGLY EXPRESSED DURING EARLY EMBRYONIC DEVELOPMENT

, 2009
Introduction and hypothesis: Iduronate-2-sulfatase (IDS) is a lysosomal enzyme responsible for the removal of the 2-sulfate group from dermatan and heparan sulfate.
ARGENTON, FRANCESCO, MODENA N, FRISO A, BORTOLUSSI M, SCARPA, MAURIZIO, MORO, ENRICO, TOMANIN R   +6 more
core  

Subtle cellular phenotypes inform pathological and benign genetic mutants in the Iduronate-2 sulfatase gene. [PDF]

Hum Mol Genet
Viswanathan A, Elia S, Le SQ, Hurt S, Doray B, Waligorski J, Kelley K, Buchser W, Dickson P.   +8 more
europepmc   +1 more source

A new route for the preparation of iduronate-2-sulfate glycosides: A new substrate for iduronate-2-sulfatase for screening and diagnosis of Mucopolysaccharidosis-II. [PDF]

Carbohydr Res
Singh G, Lim S, Wakpal J, Khaledi H, Gelb MH.   +4 more
europepmc   +1 more source

Rescue of neurologic disease in mucopolysaccharidosis type II mice via AAV-mediated liver delivery of brain-penetrating iduronate-2-sulfatase. [PDF]

Neurotherapeutics
Jin X, Ye Q, Wu X, Su J, Song L, Fu J, Xu Q, Luo M, Liu F, Ren C, Hu M, Liu M, An Y, Li Q, Li M, Yang Y.   +15 more
europepmc   +1 more source

Oral trehalose improves histological and behavior symptoms of mucopolysaccharidosis type II in iduronate 2-sulfatase deficient mice. [PDF]

Sci Rep
Lee H, Han JH, Jeong RG, Kang YJ, Choi BH, Kim SR, Cheon CK, Hur J, Lee SY.   +8 more
europepmc   +1 more source

Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II. [PDF]

Cell Death Dis, 2018
Osaki Y, Saito A, Kanemoto S, Kaneko M, Matsuhisa K, Asada R, Masaki T, Orii K, Fukao T, Tomatsu S, Imaizumi K.   +10 more
europepmc   +1 more source

Human sulfatase transiently and functionally active expressed in E. coli K12

, 2017
The recombinant human iduronate 2-sulfate sulfatase (hrIDS) was transiently and functionally active expressed in E. coli K12. The enzyme activity (crude extract) at 100 ml and 400 ml oscillated between 0.25 and 10.58 nmol h-1 mg-1.
Poutou Piñales, Raúl A., Vanegas Niño, Adriana, Landázuri, Patricia, Lareo, Leonardo, Sáenz, Homero, Barrera Avellaneda, Luis A., Echeverri Peña, Olga Yaneth   +6 more
core  

Lentiviral Gene Therapy for Mucopolysaccharidosis II with Tagged Iduronate 2-Sulfatase Prevents Life-Threatening Pathology in Peripheral Tissues But Fails to Correct Cartilage. [PDF]

Hum Gene Ther
Catalano F, Vlaar EC, Dammou Z, Katsavelis D, Huizer TF, Zundo G, Hoogeveen-Westerveld M, Oussoren E, van den Hout HJMP, Schaaf G, Pike-Overzet K, Staal FJT, van der Ploeg AT, Pijnappel WWMP.   +13 more
europepmc   +1 more source

Comparative studies of vertebrate iduronate 2-sulfatase (IDS) genes and proteins: evolution of A mammalian X-linked gene. [PDF]

3 Biotech, 2017
Holmes RS.
europepmc   +1 more source

Identification of Multiple Sulfatase Deficiency (MSD) in newborn screening: A case study. [PDF]

Mol Genet Metab Rep
Donti TR, DiPerna JC, Hegde MR, Revvity Omics, Inc.   +4 more
europepmc   +1 more source