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[Clinical study of enzyme replacement therapy with idursulfase].
Revista de neurologia, 2008Important advances have been made in enzyme replacement therapy in the treatment of lysosomal diseases over the last two decades. Here we review the initial ERT trial using idursulfase in Hunter syndrome (mucopolysaccharidosis type II) and we also examine relevant aspects of the use of this enzyme.A preclinical trial in a knockout mouse showed a ...
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