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Idursulfase: a poor risk-benefit balance in type II mucopolysaccharidosis.
Prescrire international, 2008Weekly infusions of idursulfase have no tangible benefit in boys with type II mucopolysaccharidosis who already have respiratory involvement, while hypersensitivity reactions are frequent and sometimes serious. Idursulfase should only be given to infants if they are enrolled in clinical trials.
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Biodistribution of idursulfase in cynomolgus monkeys after intrathecal-lumbar administration
Molecular Genetics and Metabolism, 2016Jou-Ku Chung +4 more
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