Cross-Species Analysis of Innate Immune Antagonism by Cytomegalovirus IE1 Protein
Viruses, 2022 The human cytomegalovirus (CMV) immediate early 1 (IE1) protein has evolved as a multifunctional antagonist of intrinsic and innate immune mechanisms. In addition, this protein serves as a transactivator and potential genome maintenance protein. Recently,
Franziska Rothemund +5 more
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Non-covalent Interaction With SUMO Enhances the Activity of Human Cytomegalovirus Protein IE1 [PDF]
Frontiers in Cell and Developmental Biology, 2021 Viruses interact with the host cellular pathways to optimize cellular conditions for replication. The Human Cytomegalovirus (HCMV) Immediate-Early protein 1 (IE1) is the first viral protein to express during infection.
Vasvi Tripathi +2 more
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LvYY1 Activates WSSV ie1 Promoter for Enhanced Vaccine Production and Efficacy [PDF]
Vaccines, 2020 The baculovirus expression vector system (BEVS) has been used as a preferred platform for the production of recombinant protein complexes and efficacious vaccines. However, limited protein yield hinders the application of BEVS.
Li-Na Tao +5 more
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Symmetric Vs Asymmetric Imide Anion Decomposition Pathways And Their Influence On Solid Electrolyte Interphase Stability For Si Anodes. [PDF]
Angew Chem Int Ed EnglSymmetric bis(flourosulfonyl)imide anions in imidazolium‐based ionic liquids direct the formation of a conformal SEI on 3D a‐Si architecture, featuring an ionorganic‐rich (LiF/LiOH) inner and Li2SO4/polymeric outer layer. This anion‐derived, mechanically robust SEI suppresses pulverization and delivers a high reversible capacity of 2489 mAh g−1 at 1C ...
Sankaran A +9 more
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The Baculovirus PE38 Protein Augments Apoptosis Induced by Transactivator IE1 [PDF]
Journal of Virology, 1999 ABSTRACT While studying apoptosis induced by baculovirus transactivator IE1 in SF-21 cells, we found that the levels of IE1-induced apoptosis were increased approximately twofold upon cotransfection with the baculovirus early pe38 gene. However, no apoptotic activity was observed in cells transfected with
Elena A. Prikhod’ko, Lois K. Miller
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Electrical engineering & Electromechanics, 2020 Purpose. Comparative analysis of energy consumption indicators of electric motors of different energy efficiency classes in an electric drive of a centrifugal pump with power of 11 kW of a water supply system with throttle regulation. Methodology.
S. Kh. Oshurbekov +4 more
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SUMO-1 Modification of Human Cytomegalovirus IE1/IE72 [PDF]
Journal of Virology, 2002 ABSTRACT Human cytomegalovirus (HCMV) immediate-early protein IE1/IE72 is involved in undermining many cellular processes including cell cycle regulation, apoptosis, nuclear architecture, and gene expression. The multifunctional nature of IE72 suggests that posttranslational modifications may modulate its activities.
Mary L. Spengler +3 more
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Evolution of an extensively antibiotic resistant sublineage of lineage 1 of GC1 Acinetobacter baumannii [PDF]
npj Antimicrobials and ResistanceThe multiply antibiotic-resistant lineage 1 of Acinetobacter baumannii global clone 1 (GC1) emerged in the 1970s, and subsequently more extensively resistant sublineages have emerged.
Christopher J. Harmer +4 more
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A promising endeavor against human cytomegalovirus: Predominant epitopes-based recombinant subunit vaccine RH<i>Ec</i><sup>IE1/pp65/pp150</sup>. [PDF]
VirulenceLi Z +10 more
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Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models. [PDF]
Mol OncolHuman cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Classon J +13 more
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